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Review Article

Diagnostic capacity of miRNAs in neonatal sepsis: a systematic review and meta-analysis

, &
Article: 2345850 | Received 04 Sep 2023, Accepted 16 Apr 2024, Published online: 07 May 2024

Figures & data

Figure 1. Flow diagram of the study selection.

Figure 1. Flow diagram of the study selection.

Figure 2. A summary of methodological qualities of included articles.

Figure 2. A summary of methodological qualities of included articles.

Table 1. Characteristics of the included studies and participants.

Figure 3. Diagnostic odds ratio of included studies.

Figure 3. Diagnostic odds ratio of included studies.

Figure 4. Forest plots of pooled sensitivity and specificity of miRNAs.

Figure 4. Forest plots of pooled sensitivity and specificity of miRNAs.

Figure 5. Heterogeneity analysis. (a) Goodness-of-fit; (b) bivariate normality; (c) influence analysis; (d) outlier detection.

Figure 5. Heterogeneity analysis. (a) Goodness-of-fit; (b) bivariate normality; (c) influence analysis; (d) outlier detection.

Figure 6. Summary receiver operating characteristic curve value of circulating miRNAs.

Figure 6. Summary receiver operating characteristic curve value of circulating miRNAs.

Table 2. Diagnostic value of circulating miRNAs and PCT.

Figure 7. Meta-regression and subgroup analysis.

Figure 7. Meta-regression and subgroup analysis.

Table 3. Summary diagnostic power based on subgroup analysis.

Figure 8. Deek’s funnel plot.

Figure 8. Deek’s funnel plot.

Data availability statement

Data availability is not applicable to this article as no new data were created or analyzed in this study.