Weight Gain is Not Associated with Antipsychotic Medication, Sociodemographic Factors, or Diagnosis in a Welsh Secure Mental Health Unit

Figures & data

Table 1. Frequency of participant demographic and clinical characteristics.

Demographic and clinical characteristics	Frequency
Patient sex	Male = 159 (76%)
	Female = 50 (24%)
Patient age	Mean = 35 years old (SD = 11.98)
	Range = 18 – 77 years old
Placement security	Medium = 135 (65%)
	Low = 74 (35%)
Primary psychiatric diagnosis	Schizophrenia = 139 (67%)
	Personality Disorder = 50 (24%)
	Mood Disorder = 20 (10%)
Substance misuse history	Yes = 125 (60%)
	No = 84 (40%)
Antipsychotic weight gain risk	High Risk = 113 (54%)
	Moderate Risk = 32 (15%)
	Low Risk = 64 (31%)
Non-antipsychotic weight gain risk	High Risk = 96 (46%)
	Low Risk = 113 (54%)

Note. Percentages are rounded to the nearest whole number.

Table 2. Weight data for sample.

	Admission	12 wk post admission
Body weight	Mean = 95.4kg (SD = 22.6)	Mean = 99.2.kg (SD = 22.5)
	Range = 43–155.2kg	Range = 53.9–180.6kg
Weight category
Underweight	N = 46 (22%)	N = 33 (16%)
	67.9kg (SD = 8.9)	74.3kg (SD = 10.5)
	Range = 43–80.5kg	Range = 53.9–96.8kg
Normal weight	N = 17 (8%)	N = 10 (5%)
	83.1kg (SD = 1.8)	87.5kg (SD = 5.9)
	Range = 80–96.6kg	Range = 74.6–99.9kg
Overweight	N = 146 (70%)	N = 163 (78%)
	105.5kg (SD = 18.6)	108.4kg (SD = 19.8)
	Range = 67.4–155.2kg	Range = 59.3–180.6kg
Psychiatric diagnosis
Schizophrenia(N = 141)	95.1kg (SD = 21.8)	98.9kg (SD = 22.1)
	Range = 51.7–149.9kg	Range = 53.9–180.6kg
Personality disorder(N = 89)	94.3 kg (SD = 23.7)	97.8kg (SD = 22.5)
	Range = 43–149.1kg	Range = 57.0–146.9kg
Mood disorder (N = 43)	100.5kg (SD = 25.2)	104.6kg (SD = 25.7)
	Range = 60.3–155.2kg	Range = 60.3–156kg

Table 3. Prevalence and direction of weight category change over 12 wk.

Weight category on admission	Weight category at 12 wk N (%)
Underweight N = 46	Underweight = 30 (65.2)
	Normal weight = 8 (17.4)
	Overweight = 8 (17.4)
Normal weight N = 17	Underweight = 1 (5.9)
	Normal weight = 5 (29.4)
	Overweight = 11 (64.7)
Overweight N = 146	Underweight = 2 (1.4)
	Normal weight = 0
	Overweight = 144 (98.6)

Note. Percentage is based on total percentage of weight category on admission.

Table 4. Multiple regression results for weight difference over 12 wk.

Weight difference (kg)	B	95% CI for B		t	SE B	β
		LL	UL
Constant	9.080*	2.642	15.518	2.781	3.264
Sex	.304	−2.079	2.687	.252	1.208	.019
Primary psychiatric diagnosis	.674	−.882	2.230	.854	.789	.066
Substance use history	−.281	−2.286	1.723	−.277	1.016	−.020
Anti-psychotic weight gain risk	.313	−.837	1.463	.537	.583	.041
Non-anti-psychotic weight gain risk	−2.673*	−4.653	−.694	−2.664	1.004	−.194
Admission bodyweight category	−1.388*	−2.558	−.219	−2.341	.593	−.169

Note. Model = “Enter” method in SPSS statistics; B = unstandardized regression coefficient; CI = confidence interval; LL = lower limit; UL = upper limit; t = t value; SE B = standard error of the coefficient; B = standardized coefficient.

* p < .01.

** p < .001.