Colchicine-induced toxicity in a heart transplant patient with chronic renal failure

Figures & data

Table 1.  Results of laboratory tests

	Days after first dose of colchicine administration
Variable	4^th–5^th day	6–7^th day	8^th day	9^th–10^th day	11^th day	12^thday
Red cell-count (10^6 per mm^3)	3.57	3.92	3.22	2.93	2.87	3.09
White cell-count (10^3 per mm^3)	11.69	15.46	6.88	2.72	2.16	9.17
•Neutrophils (10^3 per mm^3)		14.58	6.25	1.68	0.7	5.9
•Lymphocytes (10^3 per mm^3)		0.6	0.41	0.25	0.48	0.88
Platelet count (10^3 per mm^3)	191	195	122	95	96	90
C-reactive protein (mg/dl)	5.6	14.2	16.7	8.1	6.9	6.2
Calcium (mg/dl)		8.2	6.7	7.8		7.6
Phosphatemia (mg/dl)		7.4
Creatinine (mg/dl)		6	7	6	7.3	7.9
Urea nitrogen (mg/dl)		141	190	155	188	231
Aspartate aminotransferase(U/L)		775	3074	947	1271	116
Alanine aminotransferase(U/L)		376	2061	1679		684
Creatine kinase CK (U/L)	115	685	1553
Myoglobin (ng/ml)		4067	5188	3649
Troponin I (ng/ml)	0.17	0.6	0.31	0.13		0.06
Cyclosporine (ng/ml)		475		155	130
Colchicine (ng/ml)			7	6.5	5