Figures & data
Figure 1. Categories of cytokine-based nanotherapeutics for brain cancer treatment. (a) Cytokines are loaded into nanoparticles to allow a controlled release of cytokine in the targeted tissue allowing the T cell activation and consequent, cancer cell death. (b) Cytokine-functionalized nanotherapeutics allow the interaction with immune cells via cytokine receptors inducing the cancer cell death. (c) mRNA-based cytokine therapeutics are formulated to allow the intracellular delivery of mRNA-encoding cytokine and allow the cytokine translation into the cytoplasm and consequent increase of cytokine expression. Created with BioRender.com.
