Figures & data
Figure 1. Treatment with 1 μM dexamethasone (Dexa) and 1 μM triamcinolone (Triam) both suppressed proteoglycan synthesis by cultured human tenocytes, as measured by 35S-sulfate incorporation.Values represent mean (SE) percentage of control 35S-sulfate incorporation (10 subjects, with 3 replicates per subject). a p = 0.007 and b p = 0.012 compared with control (DMEM), 2-tailed Wilcoxon signed-ranks test.
Figure 2. The effect of dexamethasone on proteoglycan synthesis by human tenocytes and reversibility of the effect by PDGFBB.The results represent 35S-sulfate incorporation with DMEM alone (DMEM), treatment with 1 μM dexamethasone (Dexa), with 10 ng/mL PDGFBB (PDGF), and co-incubation with 1 μM dexamethasone and 10 ng/mL PDGFBB (Dexa+PDGF).Values represent mean (SE) percentage of control 35S-sulfate incorporation (10 subjects, with 3 replicates per subject). a p = 0.01 and b p = 0.01 compared with control. c p = 0.01 compared with 1 μM dexamethasone treatment, 2-tailed Wilcoxon signed-ranks test.
