Dysplasia epiphysealis hemimelica (Trevor's disease): 7 of our own cases and a review of the literature

Figures & data

Figure 1. Lateral and anteroposterior radiograph of the right ankle showing an irregular calcified mass on the posterior side of the talus.

Summary of our cases and those found in the literature. The locations of lesions are shown according to the numbers listed in the footnotes

A	B	C	D	E	F	G	H	I	J	K	L	M	N	O	P	Q
Trevor (1950)	M	10									+	+
	M	5					+
	M	8					+				+
	M	5					+		+	+		+
	M	7					+	+		+
	M	2					+		+
	M	3				+	+			+		+		+	+
	F	9m					+					+		+		+
Fairbank (1956)	F	2					+	+								+
	M	3									+	+
	M	5				+	+	+			+	+
	M	8								+		+
	F	6									+	+
	M	3					+
	M	10					+				+	+
	M	5										+
	M	23					+	+		+		+		+
	F	8								+		+		+		+
	M	2					+			+						+
	F	5								+		+
Kettelkamp et al. (1966)	M	28								+
	F	9								+	+	+
	F	12					+	+
	F	14					+
	M	13					+	+
	M	3								+		+
	F	14											+
	F	11									+	+
	M	15										+
	M	5					+	+		+		+		+		+
	M	11								+
	F	3					+
	M	4				+	+	+		+		+		+
	M	31					+				+	+
	M	10									+
Vanhoenacker et al. (1999)	M	7		+
Shinozaki et al. (1999)	F	33					+	+
Takagi et al. (2000)	F	8		+			+		+							+
Teixeira et al. (2001)	M	11
Nishiyama et al. (2001)	F	5					+	+
Merzoug et al. (2002)	M	3m			+	+	+	+				+
	M	13			+	+	+					+
Skripitz et al. (2003)	M	2					+	+
	M	4					+
Tschauner et al. (2004)	M	1			+	+	+	+		+	+	+
Acquaviva et al. (2005)	F	2						+
Linke et al. (2005	M	8			+
Bhosale et al. (2005)	F	8								+	+	+
	M	12
Thacker et al. (2005)	F	5							+
Our cases	M	6											+
	M	6										+
	F	6										+
	M	8										+
	M	2					+	+
	M	18				+
	M	9	+

Table

Legends to Table
A Authors
B Sex
C Age
D Scapula
E Scaphoid bone
F Acetabulum
G Proximal epiphysis of the femur
H Distal epiphysis of the femur
I Proximal epiphysis of the tibia
J Tuberositas of the tibia
K Distal epiphysis of the tibia
L Distal epiphysis of the fibula
M Talus
N Calcaneus
O Navicular bone
P Cuboid bone
Q Cuneiform bone

Figure 2. 3D CT scan showing an exostosis arising from the lateral side of the distal epiphysis of the tibia.

Figure 3. Lateral and anteroposterior radiographs of the knee showing a cloudy structure and exostosis with bone-like density at the medial side of the femur.

Figure 4. The most frequent locations of DEH in the skeleton. The numbers and percentages of occurrence in the different epiphyses (according to our data) are also given.