The effects of nail rigidity on fracture healing in rats with osteoporosis

Figures & data

Figure 1. Coronal micro-CT scan at 6 weeks. A. Low rigidity group (Ti-24Nb-4Zr-7.9Sn). B. High rigidity group (Ti-6Al-4V). The intramedullary devices have been removed for reduction of metal artifact.

Figure 2. Three-dimensional reconstruction at 12 weeks (with yellow region corresponding to ROI1). A. Low-rigidity group. B- High-rigidity group.

Bone volume (BV) and total volume (TV) in 2 regions of interest (ROI1 and ROI2), and maximum load at 6 and 12 weeks. Values represent mean (SD)

	BV (ROI1) (mm^3)	TV (ROI1) (mm^3)	BV (ROI2) (mm^3)	Maximum load (N)
6 weeks (n = 8)
Low-rigidity	75 (12)	819 (92)	327 (26)	36 (7)
High-rigidity	70 (6)	553 (40)	328 (24)	45 (9)
Difference	4 (15)	266 (72)	-2 (42)	-9 (13)
95% CI	-8–17	206–326	-37–33	-20–2
Test statistic	0.86	10	-0.11	-1.0
p-value	0.4	< 0.001	0.9	0.09
12 weeks (n = 9)
Low-rigidity	90 (9)	437 (35)	338 (23)	125 (20)
High-rigidity	78 (9)	401 (33)	303 (22)	109 (15)
Difference	12 (10)	36 (32)	34 (25)	17 (19)
95% CI	5–21	12–61	15–53	2–31
Test statistic	3.7	3.4	4.2	2.6
p-value	0.006	0.01	0.003	0.03