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Original Articles

Preparation and in vitro study of hydrochloric norvancomycin encapsulated poly (d,l-lactide-co-glycolide, PLGA) microspheres for potential use in osteomyelitis

, , , , , , & show all
Pages 1326-1330 | Received 29 Apr 2016, Accepted 02 Sep 2016, Published online: 24 Oct 2016

Figures & data

Figure 1. Scanning electron microscope micrographs of HNV-loaded PLGA microspheres.

Figure 1. Scanning electron microscope micrographs of HNV-loaded PLGA microspheres.

Figure 2. Particle size distribution of HNV-loaded PLGA microspheres.

Figure 2. Particle size distribution of HNV-loaded PLGA microspheres.

Figure 3. Detection of HNV concentration during 168 h incubation.

Figure 3. Detection of HNV concentration during 168 h incubation.

Figure 4. In vitro HNV release curve from HNV-PLGA MSs.

Figure 4. In vitro HNV release curve from HNV-PLGA MSs.

Figure 5. Antibacterial effects of HNV-PLGA MSs. Data were presented as mean ± standard deviation, * p < .05 was considered statistically significant. (A) Detection of bacteriostatic number at different concentration of HNV. (B) Detection of remaining bacterial number at different time point after incubation.

Figure 5. Antibacterial effects of HNV-PLGA MSs. Data were presented as mean ± standard deviation, * p < .05 was considered statistically significant. (A) Detection of bacteriostatic number at different concentration of HNV. (B) Detection of remaining bacterial number at different time point after incubation.

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