Figures & data
Figure 1. Entrapment efficiency of 5-FU loaded into liposomes, nanoerythrocyte membrane and hybrid erythrocyte-membrane-coated liposomes. Data expressed as M ± SD, N = 3.
Figure 2. SDS-PAGE and TEM of ghost erythrocytes, nanoerythrocyte membrane and hybrid nanoerythrocyte-membrane-coated liposomes. (Scale bar for TEM = 100 nm).
Figure 3. Phosphatidylserine exposure of the prepared formulas (A), plain nanoerythrocytes membrane (B), 5-FU loaded nanoerythrocytes membrane (C) and nanoerythrocytes membrane coated 5-FU liposome (D).
Figure 4. In vitro stability of 5-FU loaded liposome, 5-Fu-loaded nanoerythrocytes membrane, and nanoerythrocytes coated 5-FU loaded liposomes within 21 days. (A) Particle sizes. (B) Zeta potential. (C) Polydispersity index (PDI) and (D) Membrane proteins. Data expressed as M ± SD, N = 3.
Figure 5. In vitro release profiles of 5-FU solution, 5-FU liposomes, 5-FU loaded nanoerythrocytes and 5-FU liposome loaded nanoerythrocytes. Data expressed as M ± SD, N = 3.
Figure 6. Cytotoxicity studies of 5-FU liposome, 5-FU solution, 5-FU loaded nanoerythrocytes and 5-FU liposome loaded nanoerythrocytes. Data expressed as M ± SD, N = 3.
