RENAL FUNCTION CHANGES AFTER ELECTIVE CARDIAC SURGERY WITH CARDIOPULMONARY BYPASS

Figures & data

Table 1. Hemodynamic data in Phases 0, 1 and 2

	Phase 0	Phase 1	Phase 2
BPs (mm Hg)	115 ± 5	125 ± 5	125 ± 4
BPd (mmHg)	73 ± 2	65 ± 2^*	73 ± 2
P (beats/min)	66 ± 2	105 ± 4^*	89 ± 4^*

BP_s and BP_d: respectively, systolic and diastolic blood pressure. P: pulse.

^* p < 0.05 versus phase 0.

Table 2. Glomerular filtration rate in Phases 0, 1 and 2 and changes in glomerular filtration rate in Phase 1 and Phase 2 relative to Phase 0 in Group 1 and Group 2

		Phase 0	Phase 1	Phase 2
GFR	Group 1	62 ± 7	39 ± 52-3^*,#	47 ± 9
(mL/(min × 1.73 m2))	Group 2	52 ± 6	75 ± 8	73 ± 12
ΔGFR	Group 1		−39 ± 4^*	21 ± 11^*
(%)	Group 2		+55 ± 20	+88 ± 36

GFR: glomerular filtration rate. ΔGFR: change in glomerular filtration rate in Phase 1 and 2 relative to phase 0, %.

^* p < 0.01 versus Group 2

^# p < 0.05 versus Phase 0.

Table 3. Tubular function in Phases 0, 1 and 2

	Phase 0	Phase 1	Phase 2
Uosm	647 ± 52	632 ± 35	575 ± 51
UpH	5.7 ± 0.2	5.6 ± 0.2	6.1 ± 0.2
FENa	0.47 ± 0.08	1.67 ± 0.32^*	2.33 ± 1.19
FEK	16 ± 2	43 ± 5^*	29 ± 6

U_osm: urinary osmolality, mOsm/kg. U_pH: urinary pH. FE_Na and FE_K: fractional excretion of sodium and potassium, respectively, %.

^* p < 0.05 versus Phase 0.