Advanced Glycation End Products in Hemodialyzed Patients with Diabetes Mellitus Correlate with Leptin and Leptin/Body Fat Ratio

Figures & data

Table 1. Comparison of hemodialyzed patients with and without diabetes mellitus

	Hemodialyzed patients with diabetes mellitus (N = 27)	Hemodialyzed patients without diabetes mellitus (N = 35)
AGEs (AU)
Before dialysis	2.7 ± 0.7 × 10^4 a	2.2 ± 0.6 × 10^4
After dialysis	2.3 ± 0.5 × 10^4 bc	1.8 ± 0.7 × 10^4 d
Leptin (ng/mL)	25.8 ± 23.3	21.4 ± 19.8
Body fat (%)	25.4 ± 8.6	23.2 ± 9.2
Leptin/body fat	0.9 ± 0.8	0.9 ± 0.7

^ap<0.001;

^bp<0.005 vs. hemodialyzed patients without diabetes mellitus;

^cp<0.001;

^dp<0.005 vs. before dialysis.

Figure 1. Correlation of AGEs with leptin in hemodialyzed patients with diabetes mellitus. r = 0.48, p < 0.05, y = −20.92 + 0.0017 × x.

Figure 2. Correlation of AGEs with leptin in hemodialyzed patients without diabetes mellitus. r = −0.24, not significant, y = 38.728 − 0.008 × x.

Figure 3. Correlation of AGEs with leptin/body fat ration in hemodialyzed patients with diabetes mellitus. r = 0.56, p < 0.05, y = −0.9159 + 0.00007 × x.

Figure 4. Correlation of AGEs with leptin/body fat in hemodialyzed patients without diabetes mellitus. r = −0.0187, not significant, y = 0.89711 − 0.0000 × x.