Lipid Profile Before and After Renal Transplantation—A Longitudinal Study

Figures & data

Figure 1.

Table 1. Serum lipids in renal allograft recipients and healthy controls

	Mean ± S.D.
Variables/period	Patients (n = 30)	Control (n = 30)	p-value
Cholesterol total
Pretransplant (0)	152.07 ± 40.81	151.80 ± 37.94	NS
1 month post Tx	226.67 ± 48.40a		<.01
3 months post Tx	251.67 ± 57.59a		<.01
6 months post Tx	237.27 ± 38.48a		<.01
Triglycerides
Pretransplant (0)	146.60 ± 97.96	129.08 ± 49.16	NS
1 month post Tx	237.73 ± 149.84a		<.01
3 months post Tx	251.40 ± 164.74a		<.01
6 months post Tx	259.00 ± 145.74a		<.01
Cholesterol HDL
Pretransplant (0)	32.53 ± 6.01	43.52 ± 12.18	<.01
1 month post Tx	37.33 ± 7.85a		<.05
3 months post Tx	35.00 ± 10.25		<.01
6 months post Tx	36.87 ± 11.36		<.05
Cholesterol LDL
Pretransplant (0)	93.53 ± 34.80	84.20 ± 27.18	NS
1 month post Tx	145.53 ± 47.17a		<.01
3 months post Tx	162.73 ± 54.76a		<.01
6 months post Tx	152.27 ± 48.92a		<.01
Cholesterol VLDL
Pretransplant (0)	26.10 ± 6.09	24.21 ± 6.19	NS
1 month post Tx	47.84 ± 7.86a		<.01
3 months post Tx	42.93 ± 7.19a		<.01
6 months post Tx	46.50 ± 8.30a		<.01

Tx: transplantation, n = number of patients, NS = not significant, LDL = low density lipoproteins, VLDL = very low density lipoproteins.

^a<.01 when compared to pretransplant (0).

Table 2. Lipid profile in diabetics and nondiabetic patients

	Mean ± S.D.
Variables/period	Diabetic patients (n = 10)	Nondiabetic patients (n = 20)	p-value
Cholesterol total
Pretransplant (0)	173.40 ± 56.87	141.40 ± 25.52	<.05
1 month post Tx	221.80 ± 35.05a	229.10 ± 54.54a	NS
3 months post Tx	271.80 ± 42.07a	241.60 ± 62.48a	NS
6 months post Tx	245.60 ± 42.78a	233.10 ± 36.58a	NS
Triglycerides
Pretransplant (0)	236.00 ± 122.53	101.90 ± 35.02	<.01
1 month post Tx	226.40 ± 152.68	243.40 ± 152.07a	NS
3 months post Tx	234.40 ± 123.52	259.90 ± 184.31a	NS
6 months post Tx	253.20 ± 147.92	261.90 ± 148.41a	NS
Cholesterol HDL
Pretransplant (0)	36.20 ± 3.97	30.70 ± 6.09	<.05
1 month post Tx	39.60 ± 6.17	36.20 ± 8.48a	NS
3 months post Tx	32.40 ± 9.37	36.30 ± 10.64a	NS
6 months post Tx	31.20 ± 13.83	39.70 ± 9.00a	NS
Cholesterol LDL
Pretransplant (0)	105.00 ± 52.02	87.80 ± 21.50	NS
1 month post Tx	139.00 ± 48.33	148.80 ± 47.50a	NS
3 months post Tx	170.40 ± 57.29	158.9 ± 54.55a	NS
6 months post Tx	150.40 ± 48.47	153.2 ± 50.37a	NS
Cholesterol VLDL
Pretransplant (0)	27.21 ± 8.00	25.81 ± 6.01	NS
1 month post Tx	49.40 ± 10.09a	46.81 ± 11.61a	NS
3 months post Tx	43.80 ± 9.65a	42.19 ± 8.49a	NS
6 months post Tx	47.69 ± 6.81a	45.59 ± 9.51a	NS

Tx: transplantation, n = number of patients, NS = not significant, LDL = low density lipoproteins, VLDL = very low density lipoproteins.

^aValues statistically significant compared to pretransplant (0).