Antiphospholipid Antibodies in Patients with Lupus Nephritis

Figures & data

Table 1. Basic biochemical parameters of renal functions in patients with lupus nephritis

Patients	Serum urea (mmol/L) (x ± SD)	Serum creatinine (µmol/L) (x ± SD)	Creatinine clearance (ml/s) (x ± SD)	Proteinuria (g/24 h) (x ± SD)
Lupus nephritis	7.3 ± 2.8	112.7 ± 87.5	1.4 ± 0.5	0.9 ± 0.3

Table 2. Occurrence of various types of aPL in patients with lupus nephritis

aPL		Lupus nephritis (n = 22) (%)	Control group (n = 62) (%)
IgG	aCL	54a	6.5
	aPS	27a	4.8
	aPE	50a	3.2
	aPI	50a	4.8
IgM	aCL	23a	3.2
	aPS	27a	3.2
	aPE	27a	3.2
	aPI	23a	1.6

^ap<0.05 in comparison with control group, t-test of alternate separation.

Table 3. Occurrence of aPL in the patients with lupus nephritis

Patient no.	aCL IgG	aCL IgM	aPS IgG	aPS IgM	aPE IgG	aPE IgM	aPI IgG	aPI IgM
1	+		+		+		+
2							+
3					+		+
4	+				+		+
5			+		+
6	+	+		+	+	+		+
7	+				+
8
9			+		+		+
10
11	+			+
12	+		+		+
13	+					+
14	+			+
15		+		+		+	+	+
16	+	+	+	+		+	+	+
17		+	+	+	+		+	+
18	+				+	+
19	+						+
20					+			+
21	+	+		+		+	+
22

+ Positive results.

Table 4. Serum levels of anti-β₂GPI IgG and anti-oxLDL IgG in patients with lupus nephritis

Group	N	Anti-β2GPI IgG (U/mL)a	Anti-oxLDL IgG (mU/mL)
Lupus nephritis	22	10.68 ± 1.46b	746 ± 84
Control group	62	4.70 ± 0.16	500 ± 52

^ax ± SEM.

^bp<0.001, unpaired t-test.

Figure 1. Comparison of anti-β₂GPI IgG and anti-oxLDL IgG in patients with lupus nephritis.

Figure 2. Comparison of anti-β₂GPI IgG and aCL IgG in patients with lupus nephritis.