Continuous Renal Replacement Therapy (CRRT) or Intermittent Hemodialysis (IHD)—What Is the Procedure of Choice in Critically Ill Patients?

Figures & data

Table 1. Etiology of multiple organ failure and extracorporeal procedure (ECP)

Dg	IHD	CRRT	Totals
Sepsis	23	29	52
Septic shock	14	14	28
Sy. renopulmonale	4	1	5
Febris hemorrhagica	4	3	7
Rhabdomyolysis	3	2	5
Cardiomyopathia ishemica	4	3	7
All groups	52	52	104

Most of our patients with multiple organ failure (MOF) had sepsis and septic shock as a etiologic event.

Table 2. Severity scores in patients with mof on ihd/crrt (mean ± SD)

ECP	APACHE II0	MARSHAL0	SOFA0	APACHE II1	MARSHAL1	SOFA1	APACHE II2	MARSHAL2	SOFA2
IHD(N)	20.3 ± 8.4 (52)	8.8±4.0 (52)	9.8±4.7 (52)	16.6 ± 6.6 (48)	7.7 ± 5.1 (48)	8.4 ± 4.7 (48)	16.3 ± 7.3 (44)	7.3 ± 3.8 (44)	7.8 ± 4.2 (44)
CRRT(N)	21.9 ± 8.8 (52)	10.1±3.7 (52)	11.0±3.9 (52)	19.1 ± 7.9 (46)	9.1 ± 3.6 (46)	9.9 ± 3.8 (46)	18.6 ± 8.0 (43)	8.8 ± 3.9 (43)	9.7 ± 4.1 (43)
P	NS	NS	NS	NS	NS	NS	NS	NS	NS
ECP	APACHE II3	MARSHAL3	SOFA3	APACHE II7	MARSHAL7	SOFA7	APACHE II14	MARSHAL14	SOFA14
IHD(N)	16.4 ± 7.5 (44)	7.1±3.8 (44)	7.7±4.6 (44)	15.5 ± 8.2 (35)	6.1 ± 3.9 (35)	6.6 ± 4.3 (35)	13.9 ± 7.7 (24)	5.4 ± 3.7 (24)	5.9 ± 4.1 (24)
CRRT(N)	18.3 ± 8.2 (39)	8.1±3.7 (39)	9.3±7.2 (39)	18.2 ± 8.5 (31)	7.3 ± 4.1 (31)	8.5 ± 4.6 (31)	14.7 ± 6.9 (19)	6.0 ± 4.1 (19)	7.3 ± 4.7 (19)
P	NS	NS	NS	NS	NS	NS	NS	NS	NS
ECP	APACHE II21	MARSHAL21	SOFA21
IHD(N)	13.0 ± 6.4 (17)	5.1±3.2 (17)	5.4±3.2 (17)
CRRT(N)	12.7 ± 8.7 (15)	5.2±4.4 (15)	6.4±5.1 (15)
P	NS	NS	NS

In our randomized prospective study there were no differences in scoring (APACHE II, MARSHAL, SOFA) between two groups on extracorporeal procedure (ECP).

Table 3. Survival depends on extracorporeal procedure

ECP	Survivors	Dead	Total
IHD	21	31	52
CRRT	15	37	52
	36	68	104

P = NS.

There was no difference in total survival rate between two groups.

Table 4. Blood pressure instability (>10 mmHg) depends on procedure

ECP	N	Rank sum	p
HD	52	2505.0
HF	52	2955.0
Total	104		NS

There was no difference in total number of blood pressure drops between two groups.

Table 5. Survival of hemofiltration patients depends on exchanged volume

ECP	Survivors	Dead	Total
HF low	9	22	31
HF high	6	15	21
	15	37	52
p			NS

There was no difference in total survival rate between two groups.