Bone Mineral Density in Patients on Maintenance Hemodialysis and Effect of Chronic Hepatitis C Virus Infection

Figures & data

Table 1. The Patients' Clinical and Demographic Characteristics

Characteristic	HCV (−) group	HCV (+) group
Sex (male/female)	23/20	21/12
Age (years)	44.0 ± 7.8 (29–58)	44.3 ± 8.6 (25–65)
Height (cm)	162.5 ± 10.2 (130–182)	166.7 ± 9.5 (153–187)
Weight (kg)	61.1 ± 11.5 (33–85)	58.6 ± 9.5 (40–82)
Body mass index (kg/m^2)	24.1 ± 4.9 (17.6–40.8)	24.8 ± 4.3 (19.3–36.9)
Age at menarche (years)	14.1 ± 1.4 (11–16)	14.4 ± 2.2 (12–20)
Age at menopause (years)	45.9 ± 6.0 (40–57)	39.0 ± 9.5 (25–45)
Number of smokers/packages per year	167.3 ± 235.7 (0–810)	168.0 ± 217.9 (0–900)
No. of patients who had engaged in any sports activity	8/43	4/12
Average serum calcium over 1 year (mg/dL)	9.3 ± 0.6 (7.4–10.7)	9.3 ± 0.5 (8.4–10.7)
Average serum phosphorus over 1 year (mg/dL)	4.6 ± 1.0 (3.0–9.2)	4.6 ± 0.9 (3.0–7.3)
Average serum alkaline phosphatase over 1 year (U/L)	217.4 ± 86.2 (103–441)	295.4 ± 143.4 (129–646)
Average serum parathormone over 1 year (mg/dL)	149.9 ± 129.5 (11.7–567.7)	262.6 ± 188.9 (22.3–722.7)
Average erythrocyte sedimentation rate over 1 year (mm/h)	42.0 ± 15.9 (8.7–81.3)	35.6 ± 19.5 (8.0–95)
Average C‐reactive protein over 1 year (mg/L)	13.6 ± 14.0 (1.3–73.0)	11.2 ± 10.1(1.0–47.0)

Table 2. The Results of Dual X‐Ray Absorptiometry in the 76 Maintenance Hemodialysis Patients

Bone site	Anti‐HCV antibodies	T‐score mean ± SD (range)	Z‐score mean ± SD (range)	Osteopenia prevalencea (%)	Osteoporosis prevalenceb (%)
Femoral neck	(−) n = 43	− 0.8 ± 1.5 (− 3.6–3.7)	− 0.2 ± 1.2 (− 2.8–2.4)	14 (32.6%)	6 (14.0%)
	(+) n = 33	− 1.2 ± 0.9 (− 3.1–0.7)	− 0.6 ± 0.9 (− 2.2–1.1)	17 (51.5%)	4 (12.1%)
Spine L1–L4	(−) n = 43	− 0.9 ± 1.7 (− 5.0–3.6)	− 0.4 ± 1.6 (− 3.5–4.3)	16 (37.2%)	7 (16.3%)
	(+) n = 33	− 1.2 ± 1.4 (− 3.9–1.1)	− 0.6 ± 0.9 (− 2.2 ± 1.1)	10 (30.3%)	7 (21.2%)
Distal third of radius	(−) n = 43	− 2.1 ± 1.8 (− 7.6–1.7)	− 1.6 ± 1.8 (− 7.0–2.5)	19 (44.2%)	15 (34.9%)
	(+) n = 33	− 3.5 ± 1.7 [ − 6.8–(− 0.3)]	− 3.0 ± 1.7 (− 6.5–0.1)	4 (12.1%)	25 (75.8%)

^aT‐score between − 1.0 and − 2.5.

^bT‐score ≤ − 2.5.