Candidemia in children

Figures & data

Table 1.  Risk factors for candidemia in the pediatric ICU.

Risk Factor	Unadjusted Odds Ratio	Adjusted Odds Ratio	95% Confidence Interval
Presence of a central venous catheter (CVC)	33.29	30.30	3.93−233.47
Receipt of total parenteral nutrition through a CVC	79.08	61.61	7.81−486.31
Use of antibiotic with activity against anaerobic bacteria for ≥1 week	5.73	3.93	1.17−13.24
Use of vancomycin for ≥1 week	3.92	2.59	1.14−5.87
Underlying condition of malignancy	3.23	3.55	1.19−10.60

From Zaoutis, 20096.

Figure 1.  (A) Species distribution for all pediatric patients with invasive candidiasis (Abelson, 200520; Pappas, 200322; Zaoutis, 200523). (B) Species distribution by age group (Malani, 200124).

Figure 2.  Mortality associated with selected Candida spp. among younger (<13 years old; n = 144) and older (≥13 years old; n = 1447) patients with candidemia22.

Figure 3.  Trends in antifungal therapy for invasive candidiasis.

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