Diiodothyropropionic acid: WO2008106213

Abstract

The patent application WO2008106213 describes the beneficial effects of thyroid hormone analogue 3,5 diiodothyropropionic acid (DITPA) such as stimulating weight loss in overweight mammals, lowering of triglyceride and treating metabolic syndrome in humans. The human population of the patients selected in the studies mentioned has a body mass index > 25. Two examples of the human clinical studies employing DITPA have been mentioned, namely, the body weight reduction and improvement in metabolic abnormalities in obese adults.

Keywords::

• DITPA
• metabolic syndrome
• thyroid hormone receptor
• thyromimetics

Acknowledgement

I thank the management of Zydus for the encouragement and all the reviewers for their suggestions.