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Expert Opinion on Drug Delivery Volume 11, 2014 - Issue 3
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Editorial

Novel alternative therapy for spinal tuberculosis during surgery: reconstructing with anti-tuberculosis bioactivity implants

JunFeng DongHuazhong University of Science and Technology, Advanced Biomaterials and Tissue Engineering Center, Luoyu Road, 1037 Wuhan, Hubei 430074, [email protected]
, PhD,
ShengMin ZhangHuazhong University of Science and Technology, Advanced Biomaterials and Tissue Engineering Center, Luoyu Road, 1037 Wuhan, Hubei 430074, [email protected];Huazhong University of Science and Technology, Department of Biomedical Engineering, Wuhan 430074, China
, PhD,
HaoMing LiuHuazhong University of Science and Technology, Advanced Biomaterials and Tissue Engineering Center, Luoyu Road, 1037 Wuhan, Hubei 430074, [email protected]
, PhD,
XinZhi LiThree Gorges University, The Second Clinical Medical College (RenHe Hospital), Department of Orthopedics, Yiling Road, 410 Yichang, Hubei, 443001, China
, MD,
YongHui LiuHuazhong University of Science and Technology, Advanced Biomaterials and Tissue Engineering Center, Luoyu Road, 1037 Wuhan, Hubei 430074, [email protected]
, PhD &
YingYing DuHuazhong University of Science and Technology, Advanced Biomaterials and Tissue Engineering Center, Luoyu Road, 1037 Wuhan, Hubei 430074, [email protected]
, PhD
Pages 299-305 | Published online: 16 Dec 2013

Figures & data

Figure 1. Two novel reconstruction strategies for spinal tuberculosis bacterium (TB) in surgery. One is combining anti-TB drugs, poly-DL-lactide (PDLLA) and nano-hydroxyapatite (nHA) to fabricate a novel three-dimensional porous scaffold via three-dimensional printing (3DP) technology; and the other is preparing a novel titanium mesh coated with drugs/PDLLA/nHA composites by solvent evaporation and low-temperature drying technology.

Figure 1. Two novel reconstruction strategies for spinal tuberculosis bacterium (TB) in surgery. One is combining anti-TB drugs, poly-DL-lactide (PDLLA) and nano-hydroxyapatite (nHA) to fabricate a novel three-dimensional porous scaffold via three-dimensional printing (3DP) technology; and the other is preparing a novel titanium mesh coated with drugs/PDLLA/nHA composites by solvent evaporation and low-temperature drying technology.

Figure 2. The abridged general view on the relationship between four major characteristics of PDLLA/nHA/anti-TB drugs composites. Double-headed arrows mean interplay with each other. The single arrow stands for unidirectional action effect.

Figure 2. The abridged general view on the relationship between four major characteristics of PDLLA/nHA/anti-TB drugs composites. Double-headed arrows mean interplay with each other. The single arrow stands for unidirectional action effect.

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