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Expert Review of Clinical Immunology Volume 7, 2011 - Issue 6
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Perspective

Screening newborns for primary T-cell immunodeficiencies: consensus and controversy

Deborah J Accetta Pedersen Department of Pediatrics, Medical College of Wisconsin and the Children’s Research Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Department of Pediatrics, Medical College of Wisconsin and the Children’s Research Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA
,
James Verbsky Department of Pediatrics, Medical College of Wisconsin and the Children’s Research Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Department of Microbiology and Medical Genetics, Medical College of Wisconsin and the Children’s Research Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Department of Pediatrics, Medical College of Wisconsin and the Children’s Research Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Department of Microbiology and Medical Genetics, Medical College of Wisconsin and the Children’s Research Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA
&
John M Routes Department of Pediatrics, Medical College of Wisconsin and the Children’s Research Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Department of Microbiology and Medical Genetics, Medical College of Wisconsin and the Children’s Research Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA;[email protected]
Pages 761-768 | Published online: 10 Jan 2014
 
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Abstract

Newborn screening for early identification of T-cell lymphopenia and severe combined immunodeficiency has recently been recommended as an addition to the newborn screening programs in all states. This article will review the evidence supporting the use of this newborn screening test, and will outline the barriers to nationwide implementation, which include issues specific to this test and controversies regarding newborn screening in general.

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

Notes

Adapted with permission from Citation[6].

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