Completeness of breast cancer staging in the Danish Cancer Registry, 2004–2009

Figures & data

Table 1 Proportions and 95% confidence intervals for completeness of TNM registration among breast cancer patients in the Danish Cancer Registry by year of breast cancer diagnosis, gender, age group, and Charlson Comorbidity Index score

	TNM completeness		T completeness		N completeness		M completeness		Total
	%	(95% CI)	%	(95% CI)	%	(95% CI)	%	(95% CI)	n
Overall	85.4	(85.0–85.8)	94.7	(94.4–94.9)	89.6	(89.2–90.0)	89.7	(89.3–90.1)	26,488
Year of diagnosis
2004	86.0	(84.9–87.1)	94.7	(94.0–95.4)	89.3	(88.3–90.3)	91.0	(90.1–91.9)	3904
2005	86.6	(85.5–87.7)	95.6	(94.9–96.2)	89.8	(88.8–90.7)	92.1	(91.2–92.9)	3940
2006	84.8	(83.7–85.9)	95.8	(95.2–96.4)	90.0	(89.1–90.9)	89.9	(89.0–90.8)	4103
2007	85.9	(84.8–86.9)	96.0	(95.4–96.6)	90.5	(89.6–91.3)	90.9	(90.0–91.7)	4122
2008	87.0	(86.0–87.9)	95.4	(94.8–96.0)	91.3	(90.5–92.1)	90.4	(89.5–91.2)	4737
2009	82.9	(81.9–83.9)	91.6	(90.8–92.3)	87.4	(86.5–88.2)	85.5	(84.6–86.4)	5682
Gender
Female	85.4	(85.0–85.9)	94.7	(94.4–95.0)	89.6	(89.3–90.0)	89.7	(89.3–90.1)	26,350
Male	81.2	(74.0–87.0)	93.5	(88.4–96.7)	85.5	(78.9–90.6)	88.4	(82.3–92.9)	138
Age group (years)
0–39	91.3	(89.5–93.0)	96.6	(95.3–97.6)	94.9	(93.4–96.1)	94.2	(92.6–95.5)	994
40–59	91.5	(90.9–92.0)	96.7	(96.3–97.0)	95.4	(95.0–95.8)	93.5	(93.0–94.0)	9740
60–79	87.3	(86.7–87.8)	94.9	(94.5–95.3)	91.2	(90.7–91.7)	91.3	(90.8–91.8)	12,632
≥80	57.0	(55.3–58.8)	86.9	(85.7–88.1)	63.6	(61.9–65.3)	70.0	(68.4–71.6)	3122
CCI score
Low	87.9	(87.5–88.4)	95.4	(95.1–95.7)	91.9	(91.5–92.3)	91.4	(91.0–91.8)	20,274
Medium	78.8	(77.7–79.9)	93.0	(92.2–93.6)	83.8	(82.8–84.8)	84.9	(83.9–85.9)	5100
High	69.7	(67.0–72.4)	89.2	(87.3–91.0)	74.5	(71.9–77.0)	80.7	(78.3–82.9)	1114

Abbreviations: CI, confidence interval; CCI, Charlson Comorbidity Index; TNM, Tumor, Node, Metastasis classification.

Table 2 Proportions and 95% confidence intervals for staging of breast cancer patients in the Danish Cancer Registry by year of breast cancer diagnosis, gender, age group, and Charlson Comorbidity Index score

	Cancer stagea
	Localized		Regional		Distant		Unknown		Total
	%	(95% CI)	%	(95% CI)	%	(95% CI)	%	(95% CI)	n
Overall	46.0	(45.4–46.6)	39.2	(38.6–39.8)	5.2	(5.0–5.5)	9.6	(9.3–10.0)	26,488
Year of diagnosis
2004	43.2	(41.7–44.8)	41.4	(39.9–43.0)	6.4	(5.6–7.2)	9.0	(8.1–9.9)	3904
2005	43.7	(42.1–45.2)	42.3	(40.8–43.8)	6.0	(5.3–6.8)	8.0	(7.2–8.9)	3940
2006	45.2	(43.7–46.7)	40.7	(39.2–42.2)	5.2	(4.5–5.9)	8.9	(8.1–9.8)	4103
2007	44.4	(42.9–45.9)	41.4	(39.9–42.9)	5.8	(5.1–6.6)	8.3	(7.5–9.2)	4122
2008	47.5	(46.1–48.9)	38.7	(37.3–40.1)	4.7	(4.1–5.3)	9.1	(8.3–10.0)	4737
2009	49.8	(48.5–51.1)	33.2	(32.0–34.4)	3.9	(3.4–4.4)	13.1	(12.3–14.0)	5682
Gender
Female	46.0	(45.4–46.6)	39.2	(38.6–39.8)	5.2	(5.0–5.5)	9.6	(9.3–10.0)	26,350
Male	37.7	(29.9–46.0)	43.5	(35.4–51.8)	7.2	(3.8–12.5)	11.6	(7.1–17.7)	138
Age group (years)
0–39	40.1	(37.1–43.2)	49.3	(46.2–52.4)	4.0	(2.9–5.4)	6.5	(5.1–8.2)	994
40–59	45.8	(44.8–46.8)	44.9	(43.9–45.9)	3.6	(3.3–4.0)	5.7	(5.3–6.2)	9740
60–79	48.5	(47.6–49.3)	37.8	(36.9–38.6)	5.8	(5.4–6.2)	8.0	(7.5–8.5)	12,632
≥80	38.2	(36.6–40.0)	24.0	(22.6–25.6)	8.4	(7.4–9.4)	29.4	(27.8–31.0)	3122
CCI score
Low	46.2	(45.5–46.9)	40.8	(40.1–41.5)	4.9	(4.6–5.2)	8.1	(7.8–8.5)	20,274
Medium	46.2	(44.9–47.6)	34.2	(32.9–35.5)	5.8	(5.2–6.4)	13.8	(12.9–14.8)	5100
High	40.4	(37.5–43.3)	32.5	(29.8–35.3)	9.2	(7.7–11.1)	17.9	(15.7–20.2)	1114

Note:

a Based on the staging algorithm (Appendix 1).

Abbreviations: CI, confidence interval; CCI, Charlson Comorbidity Index; TNM, Tumor, Node, Metastasis classification.

Appendix Algorithm for breast cancer staging according to the TNM classification

Tumor stage
Localized	T1–4	N0	M0
	T1–2	N0	Mx
	T1	Nx	M0x
Regional	T1–4,x	N1–3	M0
Distant	Any T	Any N	M1
Unknown	T2–4,x	Nx	M0–x
	T3–4,x	N0	Mx
	T1–4,x	N1–3	Mx
	T0	N1–3	M0–1x
	T0	N0,x	M1

Note: There were six patients with T0 tumors (no evidence of primary tumor). These were all categorized in the unknown category.

Abbreviation: TNM, Tumor, Node, Metastasis.