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International Journal of Chronic Obstructive Pulmonary Disease Volume 12, 2017 - Issue
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Original Research

Clinical and economic burden of dyspnea and other COPD symptoms in a managed care setting

Judith J Stephenson1 HealthCore, Inc., Wilmington, DECorrespondence[email protected]
,
Debra Wertz1 HealthCore, Inc., Wilmington, DE
,
Tao Gu1 HealthCore, Inc., Wilmington, DE
,
Jeetvan Patel2 GlaxoSmithKline, Research Triangle Park, NC, USA
&
Anand A Dalal2 GlaxoSmithKline, Research Triangle Park, NC, USA
Pages 1947-1959 | Published online: 04 Jul 2017

Figures & data

Figure 1 Sample disposition.

Abbreviations: CAT, COPD Assessment Test; HIRD, HealthCore Integrated Research Database; mMRC, modified Medical Research Council.
Figure 1 Sample disposition.

Table 1 Patient sample demographics

Figure 2 Patient survey COPD symptom results from the (A) mMRC Dyspnea scale and (B) CATa.

Note: aPercentage values may sum up to >100 due to rounding.
Abbreviations: CAT, COPD Assessment Test; mMRC, modified Medical Research Council.
Figure 2 Patient survey COPD symptom results from the (A) mMRC Dyspnea scale and (B) CATa.

Table 2 Self-reported patient characteristics by mMRC Dyspnea scale category

Table 3 Self-reported patient characteristics by CAT COPD symptom category

Figure 3 Unadjusted COPD-related: (A) health care resource utilization and (B) health care costsa in the six-month post-survey period by mMRC or CAT COPD symptomatology.

Note: aAll costs are adjusted to 2012 US dollars.
Abbreviations: CAT, COPD Assessment Test; ER, emergency room; mMRC, modified Medical Research Council.
Figure 3 Unadjusted COPD-related: (A) health care resource utilization and (B) health care costsa in the six-month post-survey period by mMRC or CAT COPD symptomatology.

Figure 4 Generalized linear model ratios of estimated total COPD-related costs during the 6-month post-survey period of (A) patients with high dyspnea and (B) patients with high CAT COPD symptoms.

Abbreviations: CAT, COPD Assessment Test; CI, confidence interval; DCI, Deyo–Charlson Comorbidity Index; GLM, generalized linear model; mMRC, modified Medical Research Council; PPO, preferred provider organization.
Figure 4 Generalized linear model ratios of estimated total COPD-related costs during the 6-month post-survey period of (A) patients with high dyspnea and (B) patients with high CAT COPD symptoms.

Figure 5 Adjusted COPD-related total direct costs in the six-month post-survey period by mMRC Dyspnea scale symptom category and CAT COPD symptom category.

Note: P-values were calculated for the differences in total direct costs (ie, medical + pharmacy).
Abbreviations: CAT, COPD Assessment Test; mMRC, modified Medical Research Council.
Figure 5 Adjusted COPD-related total direct costs in the six-month post-survey period by mMRC Dyspnea scale symptom category and CAT COPD symptom category.
 

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