Trends and Development in the Antibiotic-Resistance of Acinetobacter baumannii: A Scientometric Research Study (1991–2019)

Figures & data

Figure 1 Annual trends in the number of antibiotic-resistant A. baumannii related publications from 1991 to 2018. The blue line is the number of annual publication. The red line is the cumulative number of publication.

Table 1 Data Type Statistics of Research on Antibiotic-Resistant A. baumannii

Rank		Types	Counts (%)	Rank	Types	Counts (%)
1		Article	3280(83.78)	7	Editorial material	30(0.766)
2		Review	496(12.669)	8	Early access	7(0.179)
3		Proceedings paper	75(1.916)	9	Correction	4(0.102)
4		Meeting abstract	44(1.124)	10	Note	1(0.026)
5		Letter	42, 1.073)	11	Retracted publication	1(0.026)
6		Book chapter	36, 0.92

Figure 2 The country co-occurrence network of antibiotic-resistant A. baumannii related publications from 1991 to 2019. A node represents a country, and node size represents frequency.

Table 2 Top 10 of Countries and Institutions That Published Antibiotic-Resistant A. baumannii-Related Articles from 1991 to 2019

Rank	Country	Counts (%)	Institute	Counts (%)
1	USA	758(19.36)	University of Sydney (Australia)	69(1.76)
2	Peoples republic of China	654(16.70)	National Taiwan University (China)	63(1.60)
3	Iran	229(5.84)	Tufts University (USA)	61(1.55)
4	India	195(4.98)	University Tehran Medical Sciences (Iran)	58(1.48)
5	Spain	174(4.44)	Zhejiang University (China)	50(1.27)
6	France	166(4.24)	National Taiwan University Hospital (China)	49(1.25)
7	Turkey	155(3.95)	Case Western Reserve University (USA)	48(1.22)
8	Australia	151(3.85)	Alfa Institute Biomed Sciences (Greece)	46(1.17)
9	Italy	150(3.83)	University Athens (Greece)	46(1.17)
10	South Korea	144(3.67)	Monash University (Australia)	42(1.07)

Figure 3 The institution co-occurrence network of antibiotic-resistant A. baumannii related publications from 1991 to 2019. A node represent an institution, and node size represents frequency.

Abbreviations: univ, university; sci, sciences; hosp, hospital; med, medical; inst, institution

Table 3 Top 10 of Author and Co-Cited Author That Published Antibiotic-Resistant A. baumannii-Related Articles from 1991 to 2019

Rank	Auther	Counts (%)	Co-Cited Author	Citations
1	Bonomo, Robert a.	49(1.25)	Falagas, M. e.	5136 (5.78)
2	Falagas, M. e.	46(1.17)	Livermore, Dm	2066(2.33)
3	Hall, Ruth m.	46(1.17)	Bonomo, Robert a.	1960(2.21)
4	Hsueh, Po-ren	32(0.81)	Towner, Kj	1483(1.67)
5	Bou, German	30(0.76)	Nordmann, Patrice	1362(1.53)
6	Rolain, Jean-marc	23(0.58)	Spellberg, Brad	1320(1.48)
7	Li, Jian	22(0.56)	Poirel, Laurent	1265(1.42)
8	Vila, Jordi	21(0.53)	Paterson, David l.	1220(1.37)
9	Pachon, Jeronimo	21(0.53)	Rolain, Jean-marc Courvalin, Patrice	1204(1.35) 987 (1.11)
10	Nordmann, Patrice	20(0.51)

Figure 4 The author co-occurrence network of antibiotic-resistant A. baumannii related publications from 1991 to 2019. A node represent an institution, and node size represents frequency.

Table 4 Top 10 Journal That Published Antibiotic-Resistant A. baumannii-Related Articles Most from 1991 to 2019

Rank	Journal	Count%	IF(2019)
1	Antimicrobial Agents and Chemotherapy	188(4.80)	4.30
2	International Journal of Antimicrobial Gents	145(3.70)	4.30
3	Journal of Antimicrobial Chemotherapy	134(3.42)	5.07
4	Plos One	105(2.68)	2.80
5	Frontiers in Microbiology	93(2.37)	4.07
6	Microbial Drug Resistance	66(1.68)	2.39
7	Clinical Microbiology and Infection	58(1.48)	6.42
8	Journal of Medical Microbiology	56(1.43)	1.37
9	American Journal of Infection Control	51(1.30)	1.97
10	BMC Infectious Diseases	49(1.25)	2.56

Table 5 Top 5 Co-Cited References Related to Antibiotic-Resistant A. baumannii Research from 1991 to 2019 in Terms of Frequency and in Terms of Centrality

Rank	Frequency	Centrality	Time	Reference	Centrality	Frequency	Time	Reference
1	449	0	2012	Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria:an international expert proposal for interim standard definitions for acquired resistance	0.32	7	1995	A novel integron-like element carrying the metallo-beta-lactamase gene blaIMP
2	444	0.01	2008	Acinetobacter baumannii: emergence of a successful pathogen.	0.31	16	1999	Spread of amikacin resistance in Acinetobacter baumannii strains isolated in Spain due to an epidemic strain.
3	226	0	2007	Global challenge of multidrug-resistant Acinetobacter baumannii.	0.28	105	2008	Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii.
4	203	0.01	2009	Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America.	0.27	24	2001	Identification of epidemic strains of Acinetobacter baumannii by integrase gene PCR
5	202	0.02	2007	An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii.	0.25	6	1997	Activity of selected beta-lactams, ciprofloxacin, and amikacin against different Acinetobacter baumannii biotypes from Chilean hospitals.

Table 6 Top 5 Cited References Related to Antibiotic-Resistant A. baumannii Research From 1991 to 2019 in Terms of Frequency

Rank	Cited	Reference
1	2743	Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal  for interim standard definitions for acquired resistance
2	1579	Origins and Evolution of Antibiotic Resistance
3	1217	Antimicrobial-ResistantPathogensAssociated With Healthcare-AssociatedInfections: AnnualSummary of DataReported tothe NationalHealthcareSafetyNetwork at the CentersFor DiseaseControl and Prevention, 2006-2007
4	1088	Acinetobacter spp, as nosocomial pathogens: Microbiological, clinical, and epidemiological features
5	869	The epidemic of antibiotic-resistant infections: A call to action for the medical community from the Infectious  Diseases Society of America

Figure 5 The reference co-occurrence network of antibiotic-resistance A. baumannii related publications from 1991 to 2019. A node represent an institution, and node size represents frequency.

Table 7 Top 10 Keywords Related to Antibiotic-Resistance A. baumannii Research from 1991 to 2019 in Terms of Frequency and in Terms of Centrality

Rank	Frequency	Centrality	Keywords	Time	Centrality	Frequency	Keywords	Time
1	1890	0.02	Acinetobacter baumannii	1994	0.24	479	Intensive care unit	1992
2	961	0.04	Pseudomonas aeruginosa	1991	0.24	351	Strain	1991
3	879	0.2	Antibiotic resistance	1991	0.2	879	Antibiotic resistance	1991
4	728	0.02	Infection	1992	0.13	426	Klebsiella pneumoniae	1993
5	673	0.08	Antimicrobial resistance	1997	0.13	303	Outbreak	1992
6	648	0.12	Escherichia coli	1991	0.12	648	Escherichia coli	1991
7	499	0.09	Epidemiology	1993	0.12	255	Nosocomial infection	1994
8	479	0.24	Intensive care unit	1992	0.09	499	Epidemiology	1993
9	426	0.13	Klebsiella pneumoniae	1993	0.09	344	Identification	1993
10	396	0.06	Resistance	1994	0.08	673	Antimicrobial resistance	1997

Figure 6 The keywords co-occurrence network of antibiotic-resistant A. baumannii related publications from 1991 to 2019. A node represents an institution, and node size represents frequency.

Figure 7 The clusters visualization network of keywords of antibiotic-resistance A. baumannii related publications from 1991 to 2019.

Figure 8 The keywords with the strongest citation bursts of antibiotic-resistant A. baumannii related publications from 1991 to 2019. The time interval is indicated by the green line, and the time interval of burst keywords is highlighted in red, indicating the beginning and end of the time interval of each burst.