Pathogenic Spectrum and Resistance Pattern of Bloodstream Infections Isolated from Postpartum Women: A Multicenter Retrospective Study

Figures & data

Table 1 Demographic Details for Postpartum Women from 2015 to 2020

Patient Characteristic	No. of Cases
Age (years)	29.3 ± 3.7
<35	223 (89.9%)
≥35	25 (10.1%)
Gestational age (weeks)	37.5 ± 4.2
<37	60 (24.2%)
≥37	188 (75.8%)
Delivery mode
Vaginal delivery	26 (10.5%)
Cesarean section	220 (88.7%)
Abortion	2 (0.8%)
Fever onset (day)	2.1 ± 1.4
Temperature	38.6 ± 0.7
PROM	118 (47.4%)
Laboratory characteristics
WBC	12.9 (10.8–15.8)
CRP	91.8 (65.4–150)
PCT	0.34 (0.18–0.75)
Pathogens
Gram-negative bacteria	214 (85.9%)
Gram-positive bacteria	34 (13.6%)
Fungus	1 (0.5%)

Abbreviations: PROM, premature rupture of membranes; WBC, white blood cell; CRP, C-reactive protein; PCT, Procalcitonin.

Figure 1 Pathogenic spectrum and distribution of BSIs during the study period. The distribution and percentages of (A) gram-negative and (B) gram-positive pathogens isolated from blood culture samples in this study.

Abbreviation: BSI, bloodstream infection.

Figure 2 Analysis of the incidence rate of E. coli and anaerobes isolated in BSIs from patients according to cesarean or vaginal delivery due to PROM. Cases of patients infected with E. coli (A) and anaerobic bacteria (B) under cesarean section (yellow) or vaginal delivery (purple) are shown. Cases of patients who underwent cesarean section or vaginal delivery due to PROM are shown.

Abbreviations: BSI, bloodstream infection; PROM, premature rupture of membranes; E. coli, Escherichia coli.

Figure 3 Changes in the pathogenic bacterial distribution in BSI from 2015 to 2020. (A) The overall distribution trend of pathogens isolated in BSIs from postpartum women between 2015 to 2020. (B) The detection of common pathogens in BSIs in recent years.

Abbreviation: BSI, bloodstream infection.

Figure 4 Sensitivity analysis of E. coli to common antibiotics.

Abbreviations: S, sensitive; I, intermediate; R, resistant; E. coli, Escherichia coli.

Figure 5 Sensitivity of E. coli to commonly used antibacterial drugs (%). (A) Sensitivity of E. coli against Ampicillin/Subatan during the past 6 years. Sensitivity of E. coli against cephalosporins including (B) Cefazolin, (C) Ceftazidime, and (D) Cefepime.

Abbreviations:E. coli, Escherichia coli. S, sensitive; I, intermediate; R, resistant.