https://orcid.org/0000-0002-2551-6420
Figures & data
Table 1 Summary of the Antibacterial Strategies
Figure 1 The targeted and combined strategies for antibacterial treatment with application of abiotic and biological nanocarriers.
Figure 2 (A) Schematic illustration of a vancomycin-loaded mannosylated nanogels (MNG-V) can be degraded by bacteria secreting phosphatase or phospholipase. (B) Schematic illustration of targeted uptake of MNG-V, transport, degradation, drug release and bacteria inhibition.
Figure 3 Schematic illustration of the fabrication of Ag@MSNs@LEVO nanoplatform and its application for a synergistic therapy of drug-resistant infections in vitro and in vivo. The silver core is the supplier of silver source, and the shell of mesoporous silica acts as the drug storage and release channel, which endows the single particle nano-platform with the ability to release antibiotics and silver tower simultaneously.
Figure 4 Schematic illustration of photothermal therapy combined with catalysis to achieve antibacterial effects and promote wound healing in vivo. PDA@Au-HAp catalyze the formation of OH from H2O2 at low concentration, enhanced photothermal antibacterial performance at 45oC via destruct cell membranes, proteins and DNA, PDA and the release of Ca2+ and PO43- promote the expression of related genes in NIH3T3 cells, facilitate the formation of granulation tissue and collagen synthesis to accelerate wound healing.
Figure 5 Schematic illustration of the working mechanism of the targeted photoactivatable nano-construct for synergistic photothermal and antibiotic treatment of S. aureus.
