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Review

Rheumatoid arthritis-associated interstitial lung disease

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Pages 21-31 | Published online: 07 Mar 2012

Figures & data

Table 1 Pulmonary manifestations of RA

Table 2 Risk factors for ILD in RA

Figure 1 High resolution computed tomography (HRCT) of RA-ILD with an NSIP pattern. An HRCT of a patient with RA showing peripheral reticulation and ground glass abnormalities with no notable honeycombing.

Abbreviations: RA, rheumatoid arthritis; ILD, interstitial lung disease; NSIP, nonspecific interstitial pneumonia.
Figure 1 High resolution computed tomography (HRCT) of RA-ILD with an NSIP pattern. An HRCT of a patient with RA showing peripheral reticulation and ground glass abnormalities with no notable honeycombing.

Figure 2 High resolution computed tomography (HRCT) of RA-ILD with a UIP pattern. An HRCT of a patient with RA showing reticulation and significant honeycombing in a basilar and peripheral distribution with an absence of significant ground glass abnormality.

Abbreviations: RA, rheumatoid arthritis; ILD, interstitial lung disease; UIP, usual interstitial pneumonia.
Figure 2 High resolution computed tomography (HRCT) of RA-ILD with a UIP pattern. An HRCT of a patient with RA showing reticulation and significant honeycombing in a basilar and peripheral distribution with an absence of significant ground glass abnormality.

Figure 3 Histopathology in a patient with RA-ILD associated NSIP. A surgical biopsy specimen in a patient with RA showing cellular interstitial infiltrates and fibrosis in a temporally uniform distribution.

Abbreviations: RA, rheumatoid arthritis; ILD, interstitial lung disease; NSIP, nonspecific interstitial pneumonia.
Figure 3 Histopathology in a patient with RA-ILD associated NSIP. A surgical biopsy specimen in a patient with RA showing cellular interstitial infiltrates and fibrosis in a temporally uniform distribution.

Figure 4 Histopathology in a patient with RA-ILD associated UIP. A surgical biopsy specimen in a patient with RA showing patchy interstitial fibrosis that starts in the peripheral acinar regions and is in close proximity to unaffected lung tissue.

Abbreviations: RA, rheumatoid arthritis; ILD, interstitial lung disease; UIP, usual interstitial pneumonia.
Figure 4 Histopathology in a patient with RA-ILD associated UIP. A surgical biopsy specimen in a patient with RA showing patchy interstitial fibrosis that starts in the peripheral acinar regions and is in close proximity to unaffected lung tissue.