Results of case-control studies support the association between contact lens use and Acanthamoeba keratitis

Figures & data

Figure 1 Flow diagram of AK studies selected.

Abbreviation: AK, Acanthamoeba keratitis.

Table 1 Results of case-control studies of keratitis caused by Acanthamoeba published from 1995 to 2012

Authors	Year	Nationality	Cases	Controls	OR	Lower 95% CI	Upper 95% CI
Radford CF et al^Citation20	1995	UK	12	378	27.64	6.46	135.54
Meier PA et al^Citation21	1998	USA	31	58	11	1.48	228.1
Joslin CE et al^Citation22	2007	USA	38	100	13.16	3.55	35.57
Verani JR et al^Citation19	2009	USA	72	140	3.57	1.86	6.87
Pacella E et al^Citation23	2012	Italy	11	703	17.68	2.25	138.89
Pooled data			164	1379	10.21	4.01	25.99

Abbreviations: OR, odds ratio; CI, confidence interval.

RadfordCFBaconASDartJKMinassianDCRisk factors for Acanthamoeba keratitis in contact lens users: a case-control studyBMJ1995310156715707787645

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MeierPAMathersWDSutphinJEFolbergRHwangTWenzelRPAn epidemic of presumed Acanthamoeba keratitis that followed regional flooding. Results of a case-control investigationArch Ophthalmol19981168109010949715690

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JoslinCETuEYShoffMEThe association of contact lens solution use and Acanthamoeba keratitisAm J Ophthalmol2007144216918017588524

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VeraniJRLorickSAYoderJSNational outbreak of Acanthamoeba keratitis associated with use of a contact lens solution, United StatesEmerg Infect Dis20091581236124219751585

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PacellaEPacellaFImpallaraDThe role of contact lenses and ocular trauma in determining Acanthamoeba keratitis: a case-control study in ItalyItal J Public Health20129197102

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