Differences in Fertility-Related Quality of Life and Emotional Status Among Women Undergoing Different IVF Treatment Cycles

Figures & data

Figure 1 Flow diagram describing the recruitment process.

Table 1 Demographic Characteristics of Women Undergoing IVF

Variables	G1 (n=192)	G2 (n=80)	G3 (n=88)	G4 (n=72)	F/χ^2	P
BMI	22.17±3.51	22.60±2.55	22.21±4.35	22.21±2.94	0.281	0.839
Age (Mean ± SD)	33.18±4.89	35.40±4.72	31.89±4.49	34.83±5.05	9.313	<0.001
Infertile duration, n (%)					41.312	<0.001
3 years or less	116 (60.4)	38 (47.5)	42 (47.7)	15 (20.8)
4 to 5 years	30 (15.6)	22 (27.5)	30 (34.1)	18 (25.0)
6 years or more	46 (24.0)	20 (25.0)	16 (18.2)	39 (54.2)
Residence, n (%)					3.359	0.340
City	112 (58.3)	44 (55.0)	46 (52.3)	32 (44.4)
Town/Rural	80 (41.7)	36 (45.0)	42 (47.7)	40 (55.6)
Educational level, n (%)					6.657	0.084
High school or below	48 (25.0)	22 (27.5)	36 (40.9)	26 (36.1)
College or above	144 (75.0)	58 (72.5)	52 (59.1)	46 (63.9)
Occupation, n (%)					12.419	0.053
Employed	104 (54.2)	54 (67.5)	60 (68.2)	44 (61.1)
Self-employed	60 (31.3)	10 (12.5)	14 (15.9)	13 (18.1)
Unemployed	28 (14.6)	16 (20.0)	14 (15.9)	15 (20.8)
Cause of infertility, n (%)					7.002	0.072
Female	48 (25.0)	20 (25.0)	32 (36.4)	27 (37.5)
Male	48 (25.0)	19 (23.8)	17 (19.3)	13 (18.1)
Others	96 (50.0)	41 (51.2)	39 (44.3)	32 (44.4)

Abbreviations: G1, women undergoing the first attempt of IVF treatment; G2, women undergoing the second attempt of IVF treatment; G3, women undergoing the third attempt of IVF treatment; G4, women undergoing the fourth or more attempt of IVF treatment.

Table 2 FertiQoL, PSSS, SAS and SDS Scores of Women Undergoing IVF

Variables	G1 (n=192)	G2 (n=80)	G3 (n=88)	G4 (n=72)	F	P
FertiQoL Total	68.93±12.08	65.68±11.64	62.70±7.28	59.15±9.22	12.764	<0.001
FertiQoL Core Module	70.81±15.20	65.21±13.61	62.95±8.69	58.09±11.64	14.733	<0.001
Core - Emotional	70.92±17.90	67.50±13.33	61.08±14.07	56.48±15.08	14.690	<0.001
Core - Mind/body	71.74±21.11	60.10±20.08	58.14±17.97	53.99±15.46	14.181	<0.001
Core - Relational	66.97±15.64	64.38±15.35	63.54±12.02	59.38±13.30	3.976	0.008
Core - Social	73.61±16.12	68.85±14.94	69.03±11.32	62.50±16.83	7.645	<0.001
FertiQoL Treatment Module	64.40±10.90	66.81±11.80	62.10±7.54	61.70±10.35	4.227	0.006
Treatment -Environment	64.71±13.88	71.15±14.45	67.99±11.43	65.39±13.11	4.036	0.008
Treatment - Tolerance	63.93±15.48	60.31±17.03	53.27±12.68	56.16±15.11	8.599	<0.001
PSSS Total	60.02±14.11	59.25±13.28	63.84±11.49	59.46±12.80	2.689	0.051
Family support	20.96±5.13	21.25±4.37	22.93±4.00	20.90±4.96	3.699	0.012
Friend support	19.66±4.92	18.95±4.86	21.18±5.15	19.32±4.75	3.348	0.019
Other support	19.41±5.10	19.05±4.87	20.02±4.48	19.24±4.71	0.651	0.583
SAS	43.23±9.15	46.22±8.20	51.99±8.43	57.26±9.72	40.172	<0.001
SDS	46.16±10.01	49.50±7.58	55.34±8.49	60.61±9.66	40.978	<0.001

Abbreviations: FertiQoL, fertility-related quality of life; PSSS, perceived social support scale; SAS, self-rating anxiety scale; SDS, self-rating depression scale; G1, women undergoing the first attempt of IVF treatment; G2, women undergoing the second attempt of IVF treatment; G3, women undergoing the third attempt of IVF treatment; G4, women undergoing the fourth or more attempt of IVF treatment.

Figure 2 Box plot of fertility-related QoL levels for each group.

Figure 3 Box plot of social support levels for each group.

Figure 4 Box plot of anxiety levels for each group.

Figure 5 Box chart of depression levels for each group.

Data Sharing Statement

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.