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Original Research

Evaluating the Prognostic Role of Monocytopenia in Chemotherapy-Induced Febrile Neutropenia Patients Treated with Granulocyte Colony-Stimulating Factor

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Pages 963-973 | Published online: 07 Sep 2021

Figures & data

Table 1 Patient’s Demographics, Malignancy Characteristics and Chemotherapy Regimens of the Selected Population

Table 2 Neutrophil Percentage, Absolute Neutrophil Count, and Absolute Neutrophil Count Difference at Several Days Following the Febrile Neutropenia Attack Treated with G-CSF

Figure 1 The short-term progression of patients with chemotherapy-induced febrile neutropenia (n=80) and subsequently treated with G-CSF illustrated by the daily change in ANC values. Patients were categorized into two groups namely monocytopenia (n=34) and non-monocytopenia (n=46) groups with a cutoff point of 0.1×109 cells/L. Data points are presented as mean ± standard error of the mean (SEM). *P-value ≤ 0.05.

Figure 1 The short-term progression of patients with chemotherapy-induced febrile neutropenia (n=80) and subsequently treated with G-CSF illustrated by the daily change in ANC values. Patients were categorized into two groups namely monocytopenia (n=34) and non-monocytopenia (n=46) groups with a cutoff point of 0.1×109 cells/L. Data points are presented as mean ± standard error of the mean (SEM). *P-value ≤ 0.05.

Figure 2 Linear regression analysis evaluated the association between AMC values at admission and ANC values at admission (A) and subsequent follow up days (B). AMC and ANC values were transformed using the natural logarithm (ln).

Figure 2 Linear regression analysis evaluated the association between AMC values at admission and ANC values at admission (A) and subsequent follow up days (B). AMC and ANC values were transformed using the natural logarithm (ln).

Figure 3 Receiver operating characteristic (ROC) curves of the AMC values at admission for prediction of ANC changes at day 1 to 6 (A-F).

Figure 3 Receiver operating characteristic (ROC) curves of the AMC values at admission for prediction of ANC changes at day 1 to 6 (A-F).

Figure 4 Kaplan–Meier curves to assess the role of monocytopenia in determining the recurrence (A) and survival (B) probability.

Figure 4 Kaplan–Meier curves to assess the role of monocytopenia in determining the recurrence (A) and survival (B) probability.