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Lung Cancer Management Volume 12, 2023 - Issue 1
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Research Article

Real-World Outcomes and Toxicity of Adjuvant Chemotherapy in NSCLC: a Single-Center Experience

Christopher Cronin1 Department of Medical Oncology,Cork University Hospital,Wilton, Co Cork, T12 EC8P, IrelandCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2715-7273View further author information
ORCID Icon,
Shahid Iqbal1 Department of Medical Oncology,Cork University Hospital,Wilton, Co Cork, T12 EC8P, IrelandView further author information
,
Abdul R Farooq1 Department of Medical Oncology,Cork University Hospital,Wilton, Co Cork, T12 EC8P, IrelandView further author information
,
Pauline O’Dea1 Department of Medical Oncology,Cork University Hospital,Wilton, Co Cork, T12 EC8P, IrelandView further author information
,
Louise Burke2 Department of Pathology,Cork University Hospital,Wilton, Co Cork, T12 EC8P, IrelandView further author information
,
Seamus O’Reilly1 Department of Medical Oncology,Cork University Hospital,Wilton, Co Cork, T12 EC8P, IrelandORCID Iconhttps://orcid.org/0000-0002-2887-7336View further author information
ORCID Icon,
Deirdre O’Mahony1 Department of Medical Oncology,Cork University Hospital,Wilton, Co Cork, T12 EC8P, IrelandView further author information
,
Derek G Power1 Department of Medical Oncology,Cork University Hospital,Wilton, Co Cork, T12 EC8P, IrelandView further author information
,
Richard M Bambury1 Department of Medical Oncology,Cork University Hospital,Wilton, Co Cork, T12 EC8P, IrelandORCID Iconhttps://orcid.org/0000-0002-2189-6972View further author information
ORCID Icon &
Dearbhaile C Collins1 Department of Medical Oncology,Cork University Hospital,Wilton, Co Cork, T12 EC8P, Ireland;3 University College Cork,College Road, Cork, T12 XF62, IrelandView further author information
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Article: LMT58 | Received 18 Aug 2022, Accepted 17 Mar 2023, Published online: 03 Apr 2023

Figures & data

Figure 1. Patient flow and stage grouping post-surgical resection of NSCLC.
Figure 1. Patient flow and stage grouping post-surgical resection of NSCLC.

Table 1. Demographic and clinical characteristics of patients who received adjuvant chemotherapy.

Table 2. Adjuvant chemotherapy regimens and associated toxicity (n = 62).

Table 3. Predictors of hospital admission and grade 3–4 hematological toxicity – outcomes by chemotherapy backbone.

Table 4. Predictors of hospital admission and grade 3–4 hematological toxicity – outcomes by histological subtype.

Figure 2. Recurrence-free survival in patients receiving adjuvant chemotherapy for resected NSCLC.
Figure 2. Recurrence-free survival in patients receiving adjuvant chemotherapy for resected NSCLC.
Figure 3. Overall survival in patients receiving adjuvant chemotherapy for resected NSCLC.
Figure 3. Overall survival in patients receiving adjuvant chemotherapy for resected NSCLC.

Table 5. Key covariates by relapse status.

Table 6. Cox proportional hazards model results for relapse-free survival.

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