Diagnosis and prognosis of congenital CMV infection: A case report and review of the literature

Figures & data

Table I. Interpretation of results of maternal and foetal laboratory findings at critical weeks of gestation.

Type of samples	Weeks of gestation	Elecsys CMV-IgG (interpretation)	Elecsys CMV-IgM (interpretation)	Elecsys CMV-IgG avidity (interpretation)	Real-time PCR copies/mL	Virus isolation
Serum	10	3.03 AU/mL positive	11.18 COI positive	20.25 % low	–	–
Serum	14	3.52 AU/mL positive	4.01 COI positive	28.82 % low	–	–
Whole blood	14	–	–	–	Negative	–
Urine	14	–	–	–	Positive < 500	–
Saliva	14	–	–	–	Positive < 500	–
Amniotic fluid	21	–	–	–	Positive 13 × 10^6	Positive

Reference values: Elecsys IgG: negative < 0; Equivocal 0.5 ≤ × < 1; positive ≥ 1. Elecsys IgM: negative < 0.7; Equivocal 0.7 ≤ × < 1; positive ≥ 1. Elecsys IgG-avidity: low < 45 %; equivocal 45 % ≤ × < 55 %; positive > 55 %.

Figure 1. Placenta with hydropic and necrotic villi. The areas of necrosis showed cytomegalic cells (arrow) and inflammatory infiltrate. Haematoxylin and eosin, original magnification × 10.