Value of a Simple Method to Assess Chronic Rejection in Renal Allograft on Electron Microscopy

Figures & data

FIGURE 1. (A) Periglomerular capillary showing 3–4 layers of lamina densa in the basement membrane (EM original 10000x). (B) Same sample of A. Detail of a glomerulus with no relevant abnormalities (EM, original 1500x).

TABLE 1. Summary of the results.

	Group A (n = 16)	Group B (n = 33)	Statistical significance p
Age (years)
Range	30–67	27–81
Mean	51.5	52.3
Time postTx (months)
Range	5–167	0–198	0.003
Mean	73	38
Follow-up (months)
Range	0–74	0–66
Mean	13	20
Tx glomerulopathy	5/15^a	0/28	0.003
C4d deposition	5/11	6/27	0.035
HCV infection	5/12	4/29	0.097
Graft loss	4/16	1/33	0.011

Time postTx, time from transplant to biopsy; Tx glomerulopathy, transplant glomerulopathy; HCV, hepatitis C virus.

^aAll fractions (n/m) indicate number of positive cases/total number of cases evaluated.