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RESEARCH ARTICLE

Magnetic nanoparticle hyperthermia for prostate cancer

, MD, PhD, FEBU, , &
Pages 790-795 | Received 24 Jan 2010, Accepted 03 Mar 2010, Published online: 23 Jul 2010

Figures & data

Figure 1. Example of an unenhanced computed tomography scan obtained one year after a single injection of magnetic fluid into the prostate, followed by six thermotherapy treatments. Hyperdense nanoparticle deposits in the prostate are still visible.

Figure 1. Example of an unenhanced computed tomography scan obtained one year after a single injection of magnetic fluid into the prostate, followed by six thermotherapy treatments. Hyperdense nanoparticle deposits in the prostate are still visible.

Figure 2. Alternating magnetic field applicator for humans (NanoActivator F100, MagForce Nanotechnologies AG, Berlin) operating at a frequency of 100 kHz and a variable field strength of 0–15 kA/m). A fibre-optic thermometry unit is part of the applicator.

Figure 2. Alternating magnetic field applicator for humans (NanoActivator F100, MagForce Nanotechnologies AG, Berlin) operating at a frequency of 100 kHz and a variable field strength of 0–15 kA/m). A fibre-optic thermometry unit is part of the applicator.

Figure 3. Histological image obtained by prostate biopsy one year after direct magnetic fluid injection into the prostate and thermal treatment. Iron-oxide nanoparticles are still present in the prostate tissue (haematoxylin-eosin staining, ×200).

Figure 3. Histological image obtained by prostate biopsy one year after direct magnetic fluid injection into the prostate and thermal treatment. Iron-oxide nanoparticles are still present in the prostate tissue (haematoxylin-eosin staining, ×200).

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