Figure 1. Estimated iron oxide concentrations required to eradicate a spherical tumour as a function of tumour radius. It is assumed that magnetic nanoparticles are uniformly distributed throughout the tumour volume. MFH calculations assume a temperature of 45 °C at the interface between tumour and healthy tissue. MagMED calculations assume a thermal dose of 18 μJ/cell required, over 2 h of AMF application, and a cell density of 2 × 108 cells/cm3.
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