771
Views
36
CrossRef citations to date
0
Altmetric
LETTER TO THE EDITOR

Progression of a caval vein thrombus in two patients with primary renal cell carcinoma on pretreatment with sunitinib

, , , , &
Pages 520-523 | Received 07 Oct 2009, Accepted 27 Nov 2009, Published online: 28 Jan 2010

Figures & data

Figure 1. CT scans of the first patient at baseline (A) and after (B) one cycle of sunitinib. A1 and B1: The primary tumour has decreased in size. A 2–3 and B 2–3: The caval vein thrombosis has increased in size (A2 and B2) and extends from infrahepatic (A2) towards the right atrium (B3). Note the absence of the thrombus in the right atrium before treatment (A3).

Figure 1. CT scans of the first patient at baseline (A) and after (B) one cycle of sunitinib. A1 and B1: The primary tumour has decreased in size. A 2–3 and B 2–3: The caval vein thrombosis has increased in size (A2 and B2) and extends from infrahepatic (A2) towards the right atrium (B3). Note the absence of the thrombus in the right atrium before treatment (A3).

Figure 2. CT scan of the primary tumour of the second patient at baseline (A) and after two cycles of sunitinib demonstrating a newly formed thrombus in the caval vein (arrows) (B).

Figure 2. CT scan of the primary tumour of the second patient at baseline (A) and after two cycles of sunitinib demonstrating a newly formed thrombus in the caval vein (arrows) (B).

Figure 3. Histology of the primary tumour (A) (H&E, 200×) and the caval vein thrombus which contains vital tumour cells of clear cell histology (B) (H&E, 100×).

Figure 3. Histology of the primary tumour (A) (H&E, 200×) and the caval vein thrombus which contains vital tumour cells of clear cell histology (B) (H&E, 100×).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.