Figure 1. The division model of CSCs: the CSC divide to produce two daughter cells, including an equal one with the self-renewal capacity and a differentiated one responsible for bulk of cells division termed transient amplifying cells. In this process, the transient amplifying cells undergo genetic changes and epigenetic alterations that make it more tissue-specific but shorter lifespan.
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.