Similarities and differences in the characteristics and primary treatment of breast cancer in men and women – a population based study (Sweden)

Figures & data

Figure 1. Overall survival in MBC patients (bottom line) and FBC patients (top line). MBC patients have a significantly worse overall survival at five years follow-up compared with FBC patients (p = 0.001). After five years results are uncertain due to few patients at risk.

Figure 2. Relative survival of MBC patients (bottom line) compared with FBC patients (top line). MBC patients have a significantly poorer relative survival at five years follow-up compared with FBC (p = 0.015). After five years results are uncertain due to few patients at risk.

Table I. Stage at diagnosis- MBC vs. FBC.

TNM classification	Males number (%) (n = 99)	Females number (%) (n = 396)	P-values (χ^2)
Tumor size			p = 0.79
T1	53 (54)	229 (58)
T2	36 (36)	123 (31)
T3	8 (8)	36 (9)
TX	2 (2)	7 (2)
Nodal status			p = 0.97
N0	52 (53)	207 (52)
N +	31 (31)	121 (31)
NX	16 (16)	68 (17)
Metastatic status			p = 0.83
M1	3 (3)	12 (3)
M0	73 (74)	303 (77)
MX	23 (23)	81 (20)
Stage			p = 0.84
I	33 (33)	147 (37)
II	41 (41)	156 (39)
III-IV	9 (9)	28 (7)
Unknown	16 (16)	65 (16)

Table II. Histopathological characteristics- MBC vs. FBC.

Histopathology	Males number (%) (n = 99)	Females number (%) (n = 396)	P-values (χ^2)
ER status			p = 0.002
Positive	69 (70)	282 (71)
Negative	5 (5)	63 (16)
Not analyzed	19 (19)	35 (9)
Data missing	6 (6)	5 (4)
PgR status			p = 0.007
Positive	59 (60)	240 (61)
Negative	15 (15)	103 (26)
Not analyzed	19 (19)	33 (8)
Data missing	6 (6)	18 (5)
Elston grade			p = 0.04
I (3–5)	11 (11)	79 (20)
II (6–7)	32 (32)	151 (38)
III (8–9)	25 (25)	65 (16)
Data missing	31 (31)	101 (26)
	n = 36	n = 144
HER2 (2003)			p = 0.51
Positive	6 (17)	15 (10)
Negative	19 (53)	88 (61)
Data missing	11 (31)	41 (28)

Table III. Adjuvant treatment- MBC vs. FBC.

Adjuvant treatment	Males number (%) (n = 99)	Females number (%) (n = 396)	P-values (χ^2)
Surgery			p < 0.001
Breast
Mastectomy	91 (92)	173 (44)
Partial mastectomy	4 (4)	199 (50)
Axilla
No axillary surgery	11 (11)	56 (14)	p = 0.43
Radiotherapy (RT)
RT	44 (55)	223 (56)	p = 0.03
Systemic adjuvant
treatment
Chemotherapy (CT)	16 (16)	82 (21)	p = 0.31
Tamoxifen and/or AI	58 (59)	206 (52)	P = 0.24
No systemic treatment	21 (21)	63 (16)	p = 0.21
CT in N +, age < 70	13 (68)	46 (73)	p = 0.70
Tam/AI in ER +, M0	51 (75)	191 (68)	p = 0.24