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Letter to the Editor

Serious gastric ulcer event after stereotactic body radiotherapy (SBRT) delivered with concomitant vinorelbine in a patient with left adrenal metastasis of lung cancer

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Pages 624-628 | Received 10 Dec 2011, Accepted 24 Feb 2012, Published online: 15 May 2012

Figures & data

Figure 1. (a) CT image of the left adrenal metastasis (arrow) before SBRT. (b) Dose distribution of SBRT. The white line indicated by arrowheads shows the 90% isodose line for the prescribed dose of 60 Gy in 10 fractions. (c) CT at 2 months after SBRT, showing partial response of the left adrenal metastasis. Deep ulceration was shown on the posterior wall (arrow) of the stomach, almost corresponding with the area in the 90% isodose line.

Figure 1. (a) CT image of the left adrenal metastasis (arrow) before SBRT. (b) Dose distribution of SBRT. The white line indicated by arrowheads shows the 90% isodose line for the prescribed dose of 60 Gy in 10 fractions. (c) CT at 2 months after SBRT, showing partial response of the left adrenal metastasis. Deep ulceration was shown on the posterior wall (arrow) of the stomach, almost corresponding with the area in the 90% isodose line.

Figure 2. Dose-volume histogram of the stomach.

Figure 2. Dose-volume histogram of the stomach.

Figure 3. Examples of the daily CT images acquired prior to beam delivery for image guidance in setting the isocenter of SBRT. (a) First treatment. (b) Fourth fraction. (c) Eighth fraction. Forms of the stomach changed slightly from day to day, but the position of the posterior wall bordering the left adrenal grand on all days seemed to remain constant.

Figure 3. Examples of the daily CT images acquired prior to beam delivery for image guidance in setting the isocenter of SBRT. (a) First treatment. (b) Fourth fraction. (c) Eighth fraction. Forms of the stomach changed slightly from day to day, but the position of the posterior wall bordering the left adrenal grand on all days seemed to remain constant.

Figure 4. Findings from gastrofiberscopy at 2.5 months after SBRT. A large, deep ulcer with necrosis was found on the posterior wall of the upper gastric body. The location of the ulcer was almost in accordance with the area in the 90% isodose line.

Figure 4. Findings from gastrofiberscopy at 2.5 months after SBRT. A large, deep ulcer with necrosis was found on the posterior wall of the upper gastric body. The location of the ulcer was almost in accordance with the area in the 90% isodose line.

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