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Acta Oncologica Volume 52, 2013 - Issue 4
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Letters to the Editor

GWAS-based association between RWDD3 and TECTA variants and paclitaxel induced neuropathy could not be confirmed in Scandinavian ovarian cancer patients

Troels K. BergmannSchool of Pharmacy, University of Queensland, Brisbane, Australia;Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, Odense, DenmarkCorrespondence[email protected]
,
Werner VachClinical Epidemiology, Institute of Medical Biometry and Medical Informatics, University Medical Center, Freiburg, Germany
,
Søren FeddersenDepartment of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark
,
Lise EckhoffDepartment of Oncology, Odense University Hospital, Odense, Denmark
,
Henrik GréenClinical Pharmacology, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden;Science for Life Laboratory, School of Biotechnology, Division of Gene Technology, Royal Institute of Technology, Solna, Sweden
,
Jørn HerrstedtDepartment of Oncology, Odense University Hospital, Odense, Denmark
&
Kim BrosenClinical Pharmacology, Institute of Public Health, University of Southern Denmark, Odense, Denmark
 show all
Pages 871-873 | Received 06 May 2012, Accepted 21 Jun 2012, Published online: 09 Aug 2012

Figures & data

Figure 1. Time to neuropathy grade 2+ by RWDD3 genotype for 239 patients treated with paclitaxel.

Figure 1. Time to neuropathy grade 2+ by RWDD3 genotype for 239 patients treated with paclitaxel.

Figure 2. Time to neuropathy grade 2+ by TECTA genotype for 239 patients treated with paclitaxel.

Figure 2. Time to neuropathy grade 2+ by TECTA genotype for 239 patients treated with paclitaxel.

Table I. Observed frequencies of patients with neuropathy grade 2+ by RWDD3 and TECTA genotype.

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