Figures & data
Figure 1. First line anti-TB drugs used in combination treatment.
Figure 2. Countries that had notified at least one case of XDR-TB by the end of 2012. Figure reproduced with kind permission from the World health Organization (Citation12).
Figure 3. Preparation of anti-TB thiazolopyridine ureas by microwave irradiation.
Figure 4. Preparation of new fluoroquinolones via microwave assisted Suzuki cross-coupling reaction.
Figure 5. a) Microwave assisted preparation of a Mtb inhibitor via Fischer indolization. b) Synthesis of Mtb inhibitors via a microwave assisted ammonolysis.
Figure 6. a) L-methionine-(SR)-sulfoximine (MSO). b) Synthesis of Mtb-GS inhibitors via a multi-step microwave assisted synthetic route. c) Microwave assisted synthesis of Mtb-GS inhibitors via multi-component heterocyclization.
Figure 7. a) Structure of fosmidomycin. b) Synthesis of fosmidomycin analogues. c) Synthesis of Mtb-IspC inhibitors via a microwave promoted oxidative Heck reaction. d) Synthesis of Mtb inhibitors via a heterocyclization.
Figure 8. Synthesis of a Mtb proteasome inhibitor under batch or continuous flow MW conditions.
Figure 9. Microwave assisted synthesis of Mtb inhibitors via a condensation reaction.
Figure 10. a) Synthesis of Mtb inhibitors via a microwave heated 5-membered heterocyclisation. b) Synthesis of Mtb inhibitors via a microwave assisted Wittig reaction. c) Synthesis of Mtb inhibitors via a microwave promoted intramolecular SNAr reaction.
