Figures & data
Table I. Studies investigating the role of D-dimer in the exclusion of atrial thrombi.
Table II. Studies reporting the prognostic value of D-dimer for cardiovascular events in AF.
Somloi M, Tomcsanyi J, Nagy E, Bodó I, Bezzegh A. D-dimer determination as a screening tool to exclude atrial thrombi in atrial fibrillation. Am J Cardiol. 2003;92:85–7. Habara S, Dote K, Kato M, Sasaki S, Goto K, Takemoto H, et al. Prediction of left atrial appendage thrombi in non-valvular atrial fibrillation. Eur Heart J. 2007;28:2217–22. Yasaka M, Miyatake K, Mitani M, Beppu S, Nagata S, Yamaguchi T, et al. Intracardiac mobile thrombus and D-dimer fragment of fibrin in patients with mitral stenosis. Br Heart J. 1991;66:22–5. Mahé I, Bergmann JF, Chassany O, dit-Sollier CB, Simoneau G, Drouet L; COAGFA Group. A multicentric prospective study in usual care: D-dimer and cardiovascular events in patients with atrial fibrillation. Thromb Res. 2012;129:693–9. Mahé I, Drouet L, Simoneau G, Minh-Muzeaux S, Caulin C, Bergmann JF. D-dimer can predict survival in patients with chronic atrial fibrillation. Blood Coagul Fibrinolysis. 2004;15:413–17. Krarup LH, Sandset EC, Sandset PM, Berge E. D-dimer levels and stroke progression in patients with acute ischemic stroke and atrial fibrillation. Acta Neurol Scand. 2011;124:40–4. Roldán V, Marín F, Muiña B, Torregrosa JM, Hernández-Romero D, Valdés M, et al. Plasma von Willebrand factor levels are an independent risk factor for adverse events including mortality and major bleeding in anticoagulated atrial fibrillation patients. J Am Coll Cardiol. 2011;57:2496–504. Sadanaga T, Sadanaga M, Ogawa S. Evidence that D-dimer levels predict subsequent thromboembolic and cardiovascular events in patients with atrial fibrillation during oral anticoagulant therapy. J Am Coll Cardiol. 2010;55:2225–31. Sadanaga T, Kohsaka S, Ogawa S. D-dimer levels in combination with clinical risk factors can effectively predict subsequent thromboembolic events in patients with atrial fibrillation during oral anticoagulant therapy. Cardiology. 2010;117:31–6. Nozawa T, Inoue H, Hirai T, Iwasa A, Okumura K, Lee JD, et al. D-dimer level influences thromboembolic events in patients with atrial fibrillation. Int J Cardiol. 2006;109:59–65. Vene N, Mavri A, Kosmelj K, Stegnar M. High D-dimer levels predict cardiovascular events in patients with chronic atrial fibrillation during oral anticoagulant therapy. Thromb Haemost. 2003;90:1163–72.