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Review Article

Imaging, genetic testing, and biomarker assessment of follicular cell-derived thyroid cancer

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Pages 409-416 | Received 28 Nov 2013, Accepted 30 Apr 2014, Published online: 02 Jul 2014

Figures & data

Figure 1. Thyroid ultrasound showing microcalcifications, poorly defined borders, and taller than wider shape.

Figure 1. Thyroid ultrasound showing microcalcifications, poorly defined borders, and taller than wider shape.

Figure 2. Diagram of intracellular pathways commonly Involved in follicular cell carcinogenesis.

Figure 2. Diagram of intracellular pathways commonly Involved in follicular cell carcinogenesis.

Figure 3. Common mutations present in thyroid carcinoma. BRAF is most commonly seen in papillary thyroid cancer (PTC), but also found in anaplastic thyroid cancer (ATC). RET/PTC rearrangements are most often in PTC. PAX8/PPARγ is mostly associated with follicular thyroid cancer (FTC), but also found in follicular variant papillary thyroid cancer (FVPTC). RAS is more common in FTC.

Figure 3. Common mutations present in thyroid carcinoma. BRAF is most commonly seen in papillary thyroid cancer (PTC), but also found in anaplastic thyroid cancer (ATC). RET/PTC rearrangements are most often in PTC. PAX8/PPARγ is mostly associated with follicular thyroid cancer (FTC), but also found in follicular variant papillary thyroid cancer (FVPTC). RAS is more common in FTC.

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