Protective effects of propofol against ischemia/reperfusion injury in rat kidneys

Figures & data

TABLE 1.  Effect of propofol treatment on morphological changes as assessed by histopathological examination of kidneys of the rats exposed to renal I/R

Groups	1	2	3	4	5	6
Congestion
Sham	+	–	–	–		–
Control	+++	++	++	++	++	+++
Intralipid	+	++	+	++	–	+
Propofol	++	–		–	–
Tubular cell swelling
Sham	–	–	–	+	–	–
Control	++	++	+	+	–	++
Intralipid	++	–	+	+	–	–
Propofol	+	++	–	–	–	+
Interstitial edema
Sham	+	–	–	–	–	–
Control	+	+	–	–	+	–
Intralipid	–	–	–	–	–	–
Propofol	–	–	–	–	–	–
Tubular dilatation
Sham	–	–	–	–	–	–
Control	++	+	–	+	–	–
Intralipid	+	+	–	+	+	–
Propofol	+	+	–	+	–	–

Notes: (−) none, (+) mild, (±) mild/none, (++) moderate, and (+++) severe.

FIGURE 1. MDA levels (nmol/mg protein).

Note: *The SOD levels of propofol were significantly lower compared to the control group (p < 0.05).

FIGURE 2. CAT levels (U/mg protein).

Note: *The CAT levels of propofol were significantly lower compared to the control group (p < 0.05).

FIGURE 3. SOD levels (U/mg protein).

Note: *The MDA levels of propofol were significantly lower compared to the control group (p < 0.05).