Mupirocin application at the exit site in peritoneal dialysis patients: five years of experience

Figures & data

FIGURE 1.  Study design of 2000–2005.

FIGURE 2.  The effect of mupirocin application on development of peritonitis. *As compared to period prior to mupirocin application.

FIGURE 3.  Comparison of once-a-week versus thrice-a-week application of mupirocin. *As compared to once-a-week application of mupirocin.

TABLE 1.  The results of the 5 years; peritonitis, ESI, microbiological analysis with antibiotic resistance patterns

	n (%)	MuR (%)	MeR (%)	Peritonitis	ESI
Group I (once-weekly mupirocin)
Coagulase-negative Staphylococcus	700 (70.56)	594 (59.87)	335 (33.7)	5	3
Staphylococcus aureus	21 (2.11)	2 (0.20)	–	–	–
Diphtheroid	94 (9.47)	–	–	1	–
Gram-negative	12 (1.2)	–	–	4	–
Others	8 (0.85)	–	–	1	1
No growth	157 (15.82)			2	3
Total: 992 samples				13	7
Group II (thrice-weekly mupirocin)
Coagulase-negative Staphylococcus	625 (72.6)	557 (64.7)	287 (33.3)	4	1
S. aureus	8 (0.93)	–	–	–	–
Diphtheroid	98 (11.3)	–	–	–	–
Gram-negative	15 (1.74)	–	–	1	–
Others	4 (0.46)	–	–	–	–
No growth	113 (13.1)	–	–	1	–
Total: 860 samples				6	1

Note: The percentages of isolates were calculated for each isolate group of total number of samplings.

TABLE 2.  Distribution of bacteria grown in swab cultures according to the site of culture

Microorganism	Nasal n (%)	Inguinal n (%)	Axillary n (%)	Exit site n (%)
Group I (once-weekly mupirocin)
Coagulase-negative Staphylococcus	186 (18)	217 (21)	214 (21)	84 (8)
Staphylococcus aureus	16 (1.6)	2 (0.2)	3 (0.3)	–
Diphtheroid	36 (3.6)	11 (1.3)	11 (1.3)	38 (3.7)
Others	9 (0.9)	4 (0.4)	9 (0.9)	2 (0.2)
No growth	1 (0.1)	14 (1.4)	11 (1.3)	125 (12)
Total: 992 samples
Group II (thrice-weekly mupirocin)
Coagulase-negative Staphylococcus	153 (17)	186 (21)	199 (22)	87 (10)
S. aureus	5 (0.5)	3 (0.3)	–	–
Diphtheroid	42 (5)	10 (1.2)	8 (0.9)	33 (4)
Others	9 (1)	5 (0.5)	1 (0.1)	4 (0.4)
No growth	6 (0.6)	11 (1.3)	7 (0.8)	91 (10)
Total: 860 samples

Note: The percentages of isolates were calculated for each isolate group of total number of samplings.