When is dialysis indicated in acute kidney injury?

Figures & data

TABLE 1.  The main studies evaluating initiation of dialysis in patients with acute kidney injury

Author	Year	Study	n	Dialysis	Criteria	Effect
Teschan^10	1960	R	15	IHD	BUN* < 200	+
Parsons^11	1961	R	33	IHD	BUN < 120–150	+
Fischer^12	1966	R	162	IHD	BUN∼150	+
Kleinknecht^13	1972	R	500	IHD	BUN < 93	+
Conger^14	1975	P	18	IHD	BUN < 70	+
Gillum^15	1986	R	34	IHD	BUN < 60	–
Gettings^16	1999	R	100	CRRT	BUN < 60	+
Bouman^21	2002	P	100	CRRT	6 hr oliguria	–
Demirkiliç^18	2004	R	61	CRRT	Diu < 100 ml/8 hr	+
Elahi^19	2004	R	64	CRRT	Diu < 100 ml/8 hr	+
Piccinni^22	2006	R	40	CRRT	12 hr ICU	+
Liu^23	2006	O	243	CRRT/IHD	BUN < 76	–

Notes: Study: R, retrospective; P, prospective; O, observational; n, number of patients; IHD, intermittent hemodialysis; CRRT, continuous renal replacement therapy; BUN*, blood nonprotein nitrogen (mg/dL); BUN, blood urea nitrogen (mg/dL); diu, diuresis; Effect (+), improved survival; effect (–), no difference.

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