Serum paraoxonase activity in patients with low glomerular filtration rates

Figures & data

TABLE 1.  Serum PON1 activity and LOOH, HDL, mean serum lipid, urea, creatinine levels, mean GFR rate values in patient and control groups

Parameters	Control (n = 40)	Patient (n = 48)	p-Value
	Mean ± SD	Mean ± SD
Age (years)	32.09 ± 6.10	31.30 ± 5.30	0.05
PONI	198 ± 91	197 ± 88	0.949
HDL	35.10 ± 3.30	34.29 ± 3.18	0.473
LOOH	15.5 ± 5.1	18.7 ± 4.0	0.026
TG (mg/dL)	100.43 ± 12.80	110.35 ± 11.33	0.009
TC (mg/dL)	156.25 ± 26.00	126.22 ± 28.05	0.520
LDL (mg/dL)	78.58 ± 10.71	83.39 ± 11.47	0.161
VLDL (mg/dL)	24.59 ± 2.68	27.43 ± 4.01	0.010
Urea	27.52 ± 10.8	37.00 ± 12.8	0.012
Creatinine	0.65 ± 0.23	1.08 ± 0.49	0.001
TGFR	101.77 ± 5.66	54.045 ± 14.20	0.000

Notes: TG, triglyceride; TC, total cholesterol; LDL, low-density lipoprotein; VLDL, very-low-density lipoprotein; TGFR, total glomerular filtration rate; PON1, serum paraoxonase; LOOH, lipid hydroperoxide; HDL, high-density lipoprotein; p < 0.05, t-test for independent samples.

FIGURE 1. The relationship between LOOH and PON1 (Spearman's correlation).