Antioxidative status and lipid peroxidation in kidney tissue of rats fed with vitamin B₆-deficient diet

Figures & data

TABLE 1.  The composition of the experimental diet

Diet (ingredients)	%	Control group (g/kg dry matter)	Vitamin B6 deficient group (g/kg dry matter)
Vitamin-free casein	70	700	700
dl-Methionine	1	10	10
Sucrose	12.3	123	123
Corn oil^a	10	100	100
Cellulose powder	2	20	20
Choline bitartrate	0.2	2	2
Vitamin mixture (AIN 76)	1	10	–
Vitamin mixture (AIN 76) (without pyridoxine-HCL)	1	–	10
Mineral mixture (AIN 76)	3.5	35	35

Note: All compounds used in the study were analytical grade.

^aUlker, Bizim corn oil (Ulker, Istanbul, Turkey).

TABLE 2.  Comparison of different variables between the study and control groups

	Control group n = 10	Vitamin B6-deficient group n = 10
GSH-Px (mIU/mg protein)	1.6 ± 0.52	2.1 ± 0.55
TSSA (U/mg protein)	46.3 ± 5.8	41.5 ± 4.5
NSSA (U/mg protein)	1.13 ± 0.06	0.96 ± 0.19
SOD (U/mg protein)	45.2 ± 2.8	40.6 ± 4.4
GST (U/mg protein)	3.2 ± 1.9	5.3 ± 1.6
GRD (U/mg protein)	1.2 ± 0.25	1.6 ± 0.33
AOP (nmol/mg protein·h^−1)	4.6 ± 0.98	3.8 ± 0.76
MDA (nmol/mg protein)	2.6 ± 0.5	3.4 ± 0.88
Plasma pyridoxal-5-phosphate (μg/L)	116.2 ± 19.8	41.8 ± 8.3**
Final body weight (g)	163.4 ± 8.9	82.3 ± 6.8**

Notes: *p < 0.05; **p < 0.001 vs. control group.

FIGURE 1. Correlations between different variables in the study group.

FIGURE 2. Correlations between different variables in the control group.