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Clinical Study

Comparison of Patient Outcome According to Renal Replacement Modality after Renal Allograft Failure

, , , , , , , , , , , , & show all
Pages 261-268 | Received 22 Aug 2010, Accepted 27 Jan 2011, Published online: 14 Mar 2011

Figures & data

Table 1. Nonimmunologic characteristics of the patients with failed allograft

Table 2. Immunologic characteristics of patients with failed allograft

Table 3. The laboratory findings and comorbidity status at renal allograft failure

Figure 1. Comparison of pre-transplant renal replacement moda- lities according to the renal replacement modality groups after allograft failure. The HD-PSKT group and ReKT group show a similar distribution of renal replacement modality before transplantation. However, in the PD-PSKT group, significantly more patients were on PD before transplantation.

Notes: HD, hemodialysis; PD, peritoneal dialysis; Preemptive, patients who underwent transplantation without dialysis; HD-PSKT, patients who started hemodialysis after allograft failure; PD-PSKT, patients who started peritoneal dialysis after allograft failure; ReKT, patients who underwent second transplantation; HD-PSKT versus ReKT, p = 0.39; HD-PSKT versus PD-PSKT, p < 0.05; PD-PSKT versus ReKT, p < 0.05.

Figure 1. Comparison of pre-transplant renal replacement moda- lities according to the renal replacement modality groups after allograft failure. The HD-PSKT group and ReKT group show a similar distribution of renal replacement modality before transplantation. However, in the PD-PSKT group, significantly more patients were on PD before transplantation.Notes: HD, hemodialysis; PD, peritoneal dialysis; Preemptive, patients who underwent transplantation without dialysis; HD-PSKT, patients who started hemodialysis after allograft failure; PD-PSKT, patients who started peritoneal dialysis after allograft failure; ReKT, patients who underwent second transplantation; HD-PSKT versus ReKT, p = 0.39; HD-PSKT versus PD-PSKT, p < 0.05; PD-PSKT versus ReKT, p < 0.05.

Table 4. The cause of death in patients after allograft failure

Figure 2. Proportions of the main causes of death according to the interval from allograft failure. Note the sudden decrease in the proportion of infection and the increase in the proportion of malignancy after 10 years.

Figure 2. Proportions of the main causes of death according to the interval from allograft failure. Note the sudden decrease in the proportion of infection and the increase in the proportion of malignancy after 10 years.

Figure 3. Comparison of patient survival rate according to the RRT group after allograft failure. The ReKT group shows a superior outcome as compared to the PD-PSKT and HD-PSKT groups. There are no significant differences between PD-PSKT and HD-PSKT groups.

Notes: RRT, renal replacement modality; HD-PSKT, patients who started hemodialysis after allograft failure; PD-PSKT, patients who started peritoneal dialysis after allograft failure; ReKT, patients who underwent second transplantation (ReKT vs. PD-PSKT, p = 0.009; ReKT vs. HD-PSKT, p = 0.00; PD-PSKT vs. HD-PSKT, p = 0.32).

Figure 3. Comparison of patient survival rate according to the RRT group after allograft failure. The ReKT group shows a superior outcome as compared to the PD-PSKT and HD-PSKT groups. There are no significant differences between PD-PSKT and HD-PSKT groups.Notes: RRT, renal replacement modality; HD-PSKT, patients who started hemodialysis after allograft failure; PD-PSKT, patients who started peritoneal dialysis after allograft failure; ReKT, patients who underwent second transplantation (ReKT vs. PD-PSKT, p = 0.009; ReKT vs. HD-PSKT, p = 0.00; PD-PSKT vs. HD-PSKT, p = 0.32).

Table 5. Variables affecting patient outcome after renal allograft failure (Cox proportional hazards analysis)

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