Relation between Pulmonary Function and Inflammatory Biomarkers in Hemodialysis Patients

Figures & data

Table 1. Serum inflammatory biomarkers levels and pulmonary function tests in hemodialysis patients in function of the etiology of the disease.

	Hypertension n = 28	Diabetes n = 22	Hypertension and diabetes n = 10	Unknown n = 28	Others n = 10	p-Value
CRP μg/mL	11.7 ± 16.5	7.9 ± 7.6	17.6 ± 15.9	9.0±14.0	20.0 ± 22.5	0.143
Albumin g/dL	3.6 ± 0.5	3.8 ± 0.3	3.8 ± 0.1	3.7 ± 0.2	3.9 ± 0.4	0.368
Ferritin μg/L	400 ± 318	387 ± 330	528 ± 496	877 ± 508	1324 ± 1256	0.071
ESR mm/h	62.3 ± 40.3	54.2 ± 31.7	56.8 ± 40.8	60.1 ± 32.6	29.8 ± 34.5	0.513
%FVC	68.3±11.6	69.4±9.9	73.6 ± 7.8	69.4 ± 14.4	65.1 ± 9.5	0.842
%FEV1	71.4±7.3	69.7±7.6	76.7 ± 6.3	76.3 ± 7.9	66.8 ± 9.8	0.075
%PEF	67.1 ± 5.8	68.2 ± 9.1	67.1 ± 6.9	71.9 ± 9.1	67.9 ± 6.2	0.519

Notes: FVC, forced vital capacity; FEV, forced expiratory volume; PEF, peak expiratory flow.

Table 2. Differences in pulmonary function tests with inflammatory biomarkers levels in serum.

	CRP (μg/mL)		Albumin (g/dL)		Ferritin (μg/mL)		ESR (mm/h)
	≥10	<10	≥3.5	<3.5	≥100	<100	≥10	<10
%FVC (mean ± SD)	63.2 ± 15.3^a	72.8 ± 5.8^a	69.9 ± 11.8	65.4 ± 9.1	67.4 ± 11.7^b	77.5 ± 4.7^b	69.6 ± 11.5	63.9 ± 10.5
%FEV1 (mean ± SD)	68.1 ± 9.7^c	75.3 ± 5.5^c	72.6 ± 8.7	71.9 ± 8.5	70.6 ± 8.2^d	76.9 ± 3.5^d	73.5 ± 7.8	66.9 ± 5.8
%PEF (mean ± SD)	64.4 ± 6.1^e	71.7 ± 7.4^e	70.7 ± 7.3	62.2 ± 3.6	69.4 ± 8.1	65.9 ± 5.8	68.8 ± 8.1	69.5 ± 4.8

Notes: FVC, forced vital capacity; FEV, forced expiratory volume; PEF, peak expiratory flow.

^a,b,c,d,ep < 0.05.