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Renal Failure Volume 34, 2012 - Issue 1
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Laboratory Study

Plasma Indoleamine 2,3-Dioxygenase Concentration is Increased in Hemodialysis Patients and May Contribute to the Pathogenesis of Coronary Heart Disease

Theodoros EleftheriadisDepartment of Nephrology, Medical School, University of Thessaly, Larissa, Greece;Research Institute, Theagenion Anticancer Hospital, Thessaloniki, GreeceCorrespondence[email protected]
,
Georgia AntoniadiDepartment of Nephrology, Medical School, University of Thessaly, Larissa, Greece
,
Vassilios LiakopoulosDepartment of Nephrology, Medical School, University of Thessaly, Larissa, Greece
,
Ioannis StefanidisDepartment of Nephrology, Medical School, University of Thessaly, Larissa, Greece
&
Grammati GalaktidouResearch Institute, Theagenion Anticancer Hospital, Thessaloniki, Greece
Pages 68-72 | Received 19 May 2011, Accepted 04 Sep 2011, Published online: 21 Oct 2011

Figures & data

Figure 1. Plasma indoleamine 2,3-dioxygenase (IDO) concentrations in hemodialysis (HD) patients and healthy volunteers.

Note: Compared with healthy volunteers, plasma IDO concentration was markedly increased in HD patients (median 48.9 ng/mL; range 112.82 ng/mL vs. median 8.04 ng/mL; range 75.46 ng/mL).

Figure 1. Plasma indoleamine 2,3-dioxygenase (IDO) concentrations in hemodialysis (HD) patients and healthy volunteers.Note: Compared with healthy volunteers, plasma IDO concentration was markedly increased in HD patients (median 48.9 ng/mL; range 112.82 ng/mL vs. median 8.04 ng/mL; range 75.46 ng/mL).

Figure 2. Plasma indoleamine 2,3-dioxygenase (IDO) concentration in hemodialysis (HD) patients with or without coronary heart disease (CHD).

Note: Compared with HD patients without CHD, plasma IDO concentration was significantly increased in HD patients with CHD (median 74.5 ng/mL; range 111.5 ng/mL vs. median 38.6 ng/mL; range 82.82 ng/mL).

Figure 2. Plasma indoleamine 2,3-dioxygenase (IDO) concentration in hemodialysis (HD) patients with or without coronary heart disease (CHD).Note: Compared with HD patients without CHD, plasma IDO concentration was significantly increased in HD patients with CHD (median 74.5 ng/mL; range 111.5 ng/mL vs. median 38.6 ng/mL; range 82.82 ng/mL).

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