The Course of Hypercalciuria and Related Markers of Bone Metabolism Parameters Associated with Corticosteroid Treatment

Figures & data

Table 1. Means, standard deviations, and p-values of all parameters.

	Baseline	Day 7	Days 30–60	After treatment	p-Value (baseline–day 7)	p-Value (baseline–days 30–60)	p-Value (day 7–days 30–60)	p-Value (baseline–after treatment)
Daily Ca output (mg/day)	98.7 ± 88.1	182.2 ± 158.6	196.9 ± 167.8	118.9 ± 90.2	<0.001	<0.001	0.30	0.72
Ca/Cre (mg/mg)	0.09 ± 0.11	0.18 ± 0.21	0.22 ± 0.21	0.1 ± 0.06	0.017	0.03	0.74	0.57
Daily Na output (mmol)	126.4 ± 72.2	161.3 ± 93.3	156.8 ± 114.5	127.8 ± 71.3	0.011	0.04	0.45	0.65
PTH (pg/mL)	75.5 ± 79.9	87.4 ± 70.9	70.1 ± 55.8	65.11 ± 54.5	0.071	0.36	0.36	0.99
Deoxypyridinoline (nmol/day)	80.8 ± 64.0	81.5 ± 64.1	139.9 ± 109.2	111.2 ± 79.7	0.91	0.003	0.02	0.12
Osteocalcin (ng/mL)	10.8 ± 19.0	6.8 ± 4.2	4.0 ± 2.9	8.1 ± 5.0	0.29	0.18	0.04	0.36
P (mg/dL)	4.2 ± 1.4	4.1 ± 1.5	4.1 ± 1.4	3.5 ± 0.7	0.60	0.36	0.97	0.20
Ca (mg/dL)	8.8 ± 0.9	8.8 ± 0.9	9.2 ± 0.7	9.5 ± 0.6	0.18	0.009	0.003	0.003
Cre (mg/dL)	0.77 ± 0.26	0.8 ± 0.3	0.7 ± 0.2	0.7 ± 0.4	0.69	0.04	0.05	0.63
ALP (U/L)	219.4 ± 85.8	210.1 ± 82.4	217.1 ± 85.9	233.4 ± 77.1	0.38	0.19	0.41	0.37

Note: Ca, calcium; Cre, creatinine; P, phosphorus; Na, sodium; ALP, alkaline phosphatase; PTH, parathyroid hormone.

Figure 1. Course of mean 24-h urinary calcium (Ca) excretion.

Figure 2. Course of mean calcium/creatinine (Ca/Cre) ratio (mg/mg).

Figure 3. Course of mean deoxypyridinoline levels (nmol/day).